Early reviews identified over 20 risk factors associated with Alzheimer's disease (AD)
including age, familial inheritance, exposure to aluminium, traumatic brain injury (TBI), and …

APOE-ε4 is best known as a risk factor for Alzheimer's disease (AD). Consequently, there is
considerable research interest in understanding whether APOE-ε4 influences cognition in …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Abstract Introduction The Alzheimer's Disease Research Summits of 2012 and 2015
incorporated experts from academia, industry, and nonprofit organizations to develop new …

The E4 allele of the ApoE gene has consistently been shown to be related to an increased
risk of Alzheimer's disease (AD). The E4 allele is also associated with functional and …

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the
gene′ s ε4 allele and risk for development of Alzheimer′ s disease (AD). However …

Cerebral small vessel disease (CSVD) refers to a spectrum of clinical and imaging findings
resulting from pathological processes of various etiologies affecting cerebral arterioles …

Alzheimer's disease (AD) is a progressive neurodegenerative disease. Although it has been
studied for years, the pathogenesis of AD is still controversial. Genetic factors may play an …

Most patients with late-onset neurodegenerative diseases such as Alzheimer's and
Parkinson's have a complex aetiology resulting from numerous genetic risk variants of small …

Cholesterol is vital to normal brain function including learning and memory but that
involvement is as complex as the synthesis, metabolism and excretion of cholesterol itself …