Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications

AR Sharma, YH Lee, A Bat-Ulzii… - Journal of …, 2022 - Springer
Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …

Ligand-directed active tumor-targeting polymeric nanoparticles for cancer chemotherapy

Y Zhong, F Meng, C Deng, Z Zhong - Biomacromolecules, 2014 - ACS Publications
In recent years, polymeric nanoparticles have appeared as a most viable and versatile
delivery system for targeted cancer therapy. Various in vivo studies have demonstrated that …

Nanoparticles and controlled delivery for bioactive compounds: Outlining challenges for new “smart-foods” for health

MC Martínez-Ballesta, Á Gil-Izquierdo… - Foods, 2018 - mdpi.com
Nanotechnology is a field of research that has been stressed as a very valuable approach
for the prevention and treatment of different human health disorders. This has been stressed …

Nanomedicine in cancer therapy

D Fan, Y Cao, M Cao, Y Wang, Y Cao… - Signal Transduction and …, 2023 - nature.com
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Vitamin E TPGS-based nanomedicine, nanotheranostics, and targeted drug delivery: past, present, and future

AK Mehata, A Setia, AK Malik, R Hassani, HG Dailah… - Pharmaceutics, 2023 - mdpi.com
It has been seventy years since a water-soluble version of vitamin E called tocophersolan
(also known as TPGS) was produced; it was approved by USFDA in 1998 as an inactive …

Polymer nanoparticles for the intravenous delivery of anticancer drugs: the checkpoints on the road from the synthesis to clinical translation

R Ferrari, M Sponchioni, M Morbidelli, D Moscatelli - Nanoscale, 2018 - pubs.rsc.org
In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …

Redox/pH dual stimuli-responsive biodegradable nanohydrogels with varying responses to dithiothreitol and glutathione for controlled drug release

YJ Pan, YY Chen, DR Wang, C Wei, J Guo, DR Lu… - Biomaterials, 2012 - Elsevier
A new type of redox/pH dual stimuli-responsive poly (methacrylic acid)(PMAA)-based
nanohydrogels was prepared from methacrylic acid and N, N-bis (acryloyl) cystamine …

Theranostic applications of nanomaterials in cancer: drug delivery, image-guided therapy, and multifunctional platforms

A Fernandez-Fernandez, R Manchanda… - Applied biochemistry …, 2011 - Springer
Successful cancer management depends on accurate diagnostics along with specific
treatment protocols. Current diagnostic techniques need to be improved to provide earlier …

The new toxicology of sophisticated materials: nanotoxicology and beyond

AD Maynard, DB Warheit, MA Philbert - Toxicological sciences, 2011 - academic.oup.com
It has long been recognized that the physical form of materials can mediate their toxicity—
the health impacts of asbestiform materials, industrial aerosols, and ambient particulate …