Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters-a review with Indian perspective
G Umamaheswaran, DK Kumar… - Indian Journal of Medical …, 2014 - journals.lww.com
Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the
absorption, distribution, metabolism as well as elimination of many therapeutic agents …
absorption, distribution, metabolism as well as elimination of many therapeutic agents …
Association between CYP2E1 polymorphisms and colorectal cancer risk: a systematic review and meta-analysis
CYP2E1 encodes an enzyme that participates in the activation of several carcinogenic
substances. Thus, numerous studies have investigated the association between CYP2E1 …
substances. Thus, numerous studies have investigated the association between CYP2E1 …
Promising targets of chrysin and daidzein in colorectal cancer: Amphiregulin, CXCL1, and MMP-9
AAA Salama, RM Allam - European journal of pharmacology, 2021 - Elsevier
Colorectal cancer is one of the primary causes of cancer-related mortality worldwide. The
tumor microenvironment contains growth factors; inflammatory chemokines, matrix …
tumor microenvironment contains growth factors; inflammatory chemokines, matrix …
[HTML][HTML] Genetic polymorphisms and pesticide-induced DNA damage: a review
The drastic increase in pesticide applications makes human exposure inevitable either
through environment or occupation. Pesticide toxicity causes many adverse health effects …
through environment or occupation. Pesticide toxicity causes many adverse health effects …
Role of genetic & environment risk factors in the aetiology of colorectal cancer in Malaysia
NH Ramzi, JK Chahil, SH Lye… - Indian Journal of …, 2014 - journals.lww.com
Methods: In this case-control study, 160 Malaysian subjects were recruited, including both
with CRC and controls. A total of 768 SNPs were genotyped and analyzed to distinguish risk …
with CRC and controls. A total of 768 SNPs were genotyped and analyzed to distinguish risk …
[HTML][HTML] Analysis of 12 variants in the development of gastric and colorectal cancers
GC Cavalcante, MAT Amador… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To evaluate the relation between 12 polymorphisms and the development of gastric
cancer (GC) and colorectal cancer (CRC). METHODS In this study, we included 125 …
cancer (GC) and colorectal cancer (CRC). METHODS In this study, we included 125 …
Genetic unraveling of colorectal cancer
Colorectal cancer is a common disease in both men and women (being the third most
common cancer in men and the second most common among women) and thus represents …
common cancer in men and the second most common among women) and thus represents …
CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
O Jiang, R Zhou, D Wu, Y Liu, W Wu, N Cheng - Tumor Biology, 2013 - Springer
Studies investigating the associations between Cytochrome P4502E1 (CYP2E1)
polymorphisms and colorectal cancer (CRC) risk report conflicting results. We conducted a …
polymorphisms and colorectal cancer (CRC) risk report conflicting results. We conducted a …
[HTML][HTML] CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
GMM Fernandes, A Russo, MA Proença… - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM To investigate the contribution of polymorphisms in the CYP1A1, CYP2E1 and EPHX1
genes on sporadic colorectal cancer (SCRC) risk. METHODS Six hundred forty-one …
genes on sporadic colorectal cancer (SCRC) risk. METHODS Six hundred forty-one …
[HTML][HTML] North India Cancer Risk: A Detailed Review with Focus on Jammu and Kashmir Demographics
Background: Cancer is a global medical challenge, and research is at its peak to understand
the unique mechanisms of cancer cells. The expanding field of epidemiology, including …
the unique mechanisms of cancer cells. The expanding field of epidemiology, including …