CMV is an ancient herpesvirus that has co-evolved with its host over millions of years. The
236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the …

Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …

Congenital cytomegalovirus (CMV) infection is the leading infectious cause of mental
retardation and hearing loss in the developed world. In recent years, there has been an …

Cytomegalovirus (CMV) is the most common congenital viral infection in the developed
world, with an overall birth prevalence of approximately 0.6%. Approximately 10% of …

Reactivation of human cytomegalovirus (HCMV) results in severe disease in AIDS patients
and immunocompromised patients receiving blood transfusions or organ or bone marrow …

Hematopoietic cells and their progenitors play important roles in human cytomegalovirus
latency and reactivation. Latent infection has been evaluated in defined populations of …

Human cytomegalovirus (HCMV) persists as a subclinical, lifelong infection in the normal
human host, maintained at least in part by its carriage in the absence of detectable infectious …

Human cytomegalovirus (HCMV) infection is largely asymptomatic in the immunocompetent
host, but remains a major cause of morbidity in immunosuppressed individuals. Using the …

Human cytomegalovirus (HCMV) infection remains a major cause of morbidity in patient
populations. In certain clinical settings, it is the reactivation of the pre‐existing latent infection …

Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …