Summary of information on human CYP enzymes: human P450 metabolism data

S Rendic - Drug metabolism reviews, 2002 - Taylor & Francis
This chapter is an update of the data on substrates, reactions, inducers, and inhibitors of
human CYP enzymes published previously by Rendic and DiCarlo Citation 1a, Citation 1b …

Estrogen signaling: An emanating therapeutic target for breast cancer treatment

T Saha, S Makar, R Swetha, G Gutti… - European journal of …, 2019 - Elsevier
Breast cancer, a most common malignancy in women, was known to be associated with
steroid hormone estrogen. The discovery of estrogen receptor (ER) gave us not only a …

Recent progress in synthesis and bioactivity studies of indolizines

GS Singh, EE Mmatli - European journal of medicinal chemistry, 2011 - Elsevier
The present review describes the recent progress in synthetic approaches to construct
indolizine framework (including partially or wholly reduced ring) and the design of such …

Indolizine: a biologically active moiety

V Sharma, V Kumar - Medicinal Chemistry Research, 2014 - Springer
The discovery of camptothecin and its analogs was the major breakthrough through which
“Indolizine moiety” came into limelight. Although major part of the research on indolizine …

Nucleophilic dearomatization of activated pyridines

G Bertuzzi, L Bernardi, M Fochi - Catalysts, 2018 - mdpi.com
Amongst nitrogen heterocycles of different ring sizes and oxidation statuses,
dihydropyridines (DHP) occupy a prominent role due to their synthetic versatility and …

Amberlite–IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1, 2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of …

A Hazra, S Mondal, A Maity, S Naskar, P Saha… - European journal of …, 2011 - Elsevier
A number of indolizines and pyrrolo [1, 2-a] quinolines/isoquinolines were prepared from
phenacyl pyridinium, quinolinium and isoquinolinium salts derived fromthe reaction of the …

Synthesis, Characterization, Molecular Docking, Acetylcholinesterase and α‐Glycosidase Inhibition Profiles of Nitrogen‐Based Novel Heterocyclic Compounds

İ Gulcin, OV Petrova, P Taslimi, SF Malysheva… - …, 2022 - Wiley Online Library
In this study, a series of nitrogen‐based novel heterocyclic compounds were synthesized
and characterized by elemental analysis, IR and NMR spectra. The novel synthesized …

Palladium-catalyzed intermolecular aminocarbonylation of alkenes: efficient access of β-amino acid derivatives

J Cheng, X Qi, M Li, P Chen, G Liu - Journal of the American …, 2015 - ACS Publications
A novel palladium-catalyzed intermolecular aminocarbonylation of alkenes has been
developed in which the employment of hypervalent iodine reagent can accelerate the …

Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition

SCB Gnoatto, A Dassonville-Klimpt… - European journal of …, 2008 - Elsevier
The inhibitory potency of ursolic acid extracted from Ilex paraguariensis, a plant used in
South American population for a tea preparation known as maté, and its derivatives to inhibit …

Cobalt (II) Porphyrin‐Catalyzed Intramolecular Cyclopropanation of N‐Alkyl Indoles/Pyrroles with Alkylcarbene: Efficient Synthesis of Polycyclic N‐Heterocycles

AR Reddy, F Hao, K Wu, CY Zhou… - Angewandte Chemie …, 2016 - Wiley Online Library
A protocol on chemoselective cobalt (II) porphyrin‐catalyzed intramolecular
cyclopropanation of N‐alkyl indoles/pyrroles with alkylcarbenes has been developed. The …