NF-κB in monocytes and macrophages–an inflammatory master regulator in multitalented immune cells

M Mussbacher, M Derler, J Basílio… - Frontiers in …, 2023 - frontiersin.org
Nuclear factor κB (NF-κB) is a dimeric transcription factor constituted by two of five protein
family members. It plays an essential role in inflammation and immunity by regulating the …

Novel bioactive compounds from marine sources as a tool for functional food development

S Ghosh, T Sarkar, S Pati, ZA Kari, HA Edinur… - Frontiers in Marine …, 2022 - frontiersin.org
The marine environment is a relatively unexplored source of functional ingredients that can
be used in food processing, storage, and fortification in a variety of ways. Marine …

Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2

CM Su, L Wang, D Yoo - Scientific reports, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for
coronavirus disease 2019 (COVID-19) that emerged in human populations recently …

Mechanisms linking inflammation to insulin resistance

L Chen, R Chen, H Wang… - International journal of …, 2015 - Wiley Online Library
Obesity is now widespread around the world. Obesity‐associated chronic low‐grade
inflammation is responsible for the decrease of insulin sensitivity, which makes obesity a …

[HTML][HTML] Efficacy of glutathione therapy in relieving dyspnea associated with COVID-19 pneumonia: A report of 2 cases

RI Horowitz, PR Freeman, J Bruzzese - Respiratory medicine case reports, 2020 - Elsevier
Purpose Infection with COVID-19 potentially can result in severe outcomes and death from
“cytokine storm syndrome”, resulting in novel coronavirus pneumonia (NCP) with severe …

Intracellular pathogens: host immunity and microbial persistence strategies

A Thakur, H Mikkelsen… - Journal of immunology …, 2019 - Wiley Online Library
Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

Inflammatory biomarkers on an LPS-induced RAW 264.7 cell model: A systematic review and meta-analysis

BM Facchin, GO Dos Reis, GN Vieira, ETB Mohr… - Inflammation …, 2022 - Springer
Introduction Several experimental models have been designed to promote the development
of new anti-inflammatory drugs. The in vitro model using RAW 264.7 cells has been widely …

RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8+ T cells

N Yatim, H Jusforgues-Saklani, S Orozco, O Schulz… - Science, 2015 - science.org
Dying cells initiate adaptive immunity by providing both antigens and inflammatory stimuli for
dendritic cells, which in turn activate CD8+ T cells through a process called antigen cross …

The NF-κB signaling pathway, the microbiota, and gastrointestinal tumorigenesis: recent advances

C Peng, Y Ouyang, N Lu, N Li - Frontiers in Immunology, 2020 - frontiersin.org
Gastrointestinal (GI) cancers, especially gastric cancer and colorectal cancer (CRC),
represent a major global health burden. A large population of microorganisms residing in …

A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease

Z Chen, R Yu, Y **ong, F Du, S Zhu - Lipids in health and disease, 2017 - Springer
Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of diseases, including
simple steatosis, nonalcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular …