Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

New directions in therapeutic angiogenesis and arteriogenesis in peripheral arterial disease

BH Annex, JP Cooke - Circulation research, 2021 - Am Heart Assoc
The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

[HTML][HTML] Global vascular guidelines on the management of chronic limb-threatening ischemia

MS Conte, AW Bradbury, P Kolh, JV White… - European Journal of …, 2019 - Elsevier
Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

Wound healing properties of flavonoids: A systematic review highlighting the mechanisms of action

MTB Carvalho, HG Araújo-Filho, AS Barreto… - Phytomedicine, 2021 - Elsevier
Background Flavonoids are a class of compounds with a wide variety of biological functions,
being an important source of new products with pharmaceutical potential, including …

Overexpression of VEGF in dermal fibroblast cells accelerates the angiogenesis and wound healing function: in vitro and in vivo studies

F Shams, H Moravvej, S Hosseinzadeh, E Mostafavi… - Scientific reports, 2022 - nature.com
Fibroblasts are the main cells of connective tissue and have pivotal roles in the proliferative
and maturation phases of wound healing. These cells can secrete various cytokines, growth …

Functional human vascular network generated in photocrosslinkable gelatin methacrylate hydrogels

YC Chen, RZ Lin, H Qi, Y Yang, H Bae… - Advanced functional …, 2012 - Wiley Online Library
The generation of functional, 3D vascular networks is a fundamental prerequisite for the
development of many future tissue engineering‐based therapies. Current approaches in …

Isolation of putative progenitor endothelial cells for angiogenesis

T Asahara, T Murohara, A Sullivan, M Silver… - Science, 1997 - science.org
Putative endothelial cell (EC) progenitors or angioblasts were isolated from human
peripheral blood by magnetic bead selection on the basis of cell surface antigen expression …

The biology of vascular endothelial growth factor

N Ferrara, T Davis-Smyth - Endocrine reviews, 1997 - academic.oup.com
Biology of Vascular Endothelial Growth Factor | Endocrine Reviews | Oxford Academic Skip to
Main Content Advertisement Oxford Academic Journals Books Search Menu Information …

Vascular endothelial growth factor: basic science and clinical progress

N Ferrara - Endocrine reviews, 2004 - academic.oup.com
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization

T Asahara, H Masuda, T Takahashi, C Kalka… - Circulation …, 1999 - Am Heart Assoc
Circulating endothelial progenitor cells (EPCs) have been isolated in peripheral blood of
adult species. To determine the origin and role of EPCs contributing to postnatal …