Nasal sprays and behavioural interventions compared with usual care for acute respiratory illness in primary care: a randomised, controlled, open-label, parallel …
P Little, J Vennik, K Rumsby, B Stuart… - The Lancet …, 2024 - thelancet.com
Background A small amount of evidence suggests that nasal sprays, or physical activity and
stress management, could shorten the duration of respiratory infections. This study aimed to …
stress management, could shorten the duration of respiratory infections. This study aimed to …
Toward a Radically Simple Multi‐Modal Nasal Spray for Preventing Respiratory Infections
Nasal sprays for pre‐exposure prophylaxis against respiratory infections show limited
protection (20–70%), largely due to their single mechanism of action—either neutralizing …
protection (20–70%), largely due to their single mechanism of action—either neutralizing …
[HTML][HTML] Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections
The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems,
using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta …
using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta …
Determining the clinical and cost-effectiveness of nasal sprays and a physical activity and stress management intervention to reduce respiratory tract infections in …
Background Most adults in the UK experience at least one viral respiratory tract infection
(RTI) per year. Individuals with comorbidities and those with recurrent RTIs are at higher risk …
(RTI) per year. Individuals with comorbidities and those with recurrent RTIs are at higher risk …
Effects of Nozzle Retraction Elimination on Spray Distribution in Middle-Posterior Turbinate Regions: A Comparative Study
The standard multi-dose nasal spray pump features an integrated actuator and nozzle,
which inevitably causes a retraction of the nozzle tip during application. The retraction stroke …
which inevitably causes a retraction of the nozzle tip during application. The retraction stroke …
Seawater nasal wash to reduce symptom duration and viral load in COVID-19 and upper respiratory tract infections: a randomized controlled multicenter trial
L de Gabory, S Vallet, G Naelten… - European Archives of …, 2024 - Springer
Purpose The objective was to assess the efficacy of seawater nasal wash on symptom
duration, intranasal viral load, household transmission in COVID-19 and URTIs. Methods …
duration, intranasal viral load, household transmission in COVID-19 and URTIs. Methods …
In Situ Gelling Behavior and Biopharmaceutical Characterization of Nano-Silver-Loaded Poloxamer Matrices Designed for Nasal Drug Delivery
A combination of Poloxamer 407 (P407) and hydroxypropyl methylcellulose (HPMC)
hydrosols is proposed as an in situ thermo-gelling vehicle for the nasal drug delivery of …
hydrosols is proposed as an in situ thermo-gelling vehicle for the nasal drug delivery of …
A randomised multi-arm, open label trial of nasal sprays and a behavioural intervention for acute respiratory illness in primary care: a randomised, controlled, open …
P Little, J Vennik, K Rumsby, T Becque… - The Lancet …, 2024 - eprints.soton.ac.uk
Background: limited evidence suggests that nasal sprays, or physical activity and stress-
management, could limit respiratory infections. This study aimed to assess the impact on …
management, could limit respiratory infections. This study aimed to assess the impact on …
Functionalized protein microparticles targeting hACE2 as a novel preventive strategy for SARS-CoV-2 infection
Y Li, Y Huang, K Zhu, X Duan, S Li, M Xu… - International Journal of …, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in a serious burden on public …
respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in a serious burden on public …
A Drug-Free Pathogen Capture and Neutralizing Nasal Spray to Prevent Emerging Respiratory Infections
Respiratory infections pose a global health crisis. Vaccines are pathogen specific, and new
vaccines are needed for mutants and emerging pathogens. Here, we report a “drug free” …
vaccines are needed for mutants and emerging pathogens. Here, we report a “drug free” …