Rho GTPases in the physiology and pathophysiology of peripheral sensory neurons
Numerous experimental studies demonstrate that the Ras homolog family of guanosine
triphosphate hydrolases (Rho GTPases) Ras homolog family member A (RhoA), Ras-related …
triphosphate hydrolases (Rho GTPases) Ras homolog family member A (RhoA), Ras-related …
Cullin 3-based ubiquitin ligases as master regulators of mammalian cell differentiation
W Dubiel, D Dubiel, DA Wolf, M Naumann - Trends in biochemical …, 2018 - cell.com
Specificity of the ubiquitin proteasome system is controlled by ubiquitin E3 ligases, including
their major representatives, the multisubunit cullin-RING ubiquitin (Ub) ligases (CRLs). More …
their major representatives, the multisubunit cullin-RING ubiquitin (Ub) ligases (CRLs). More …
Cdk1 activates pre-mitotic nuclear envelope dynein recruitment and apical nuclear migration in neural stem cells
AD Baffet, DJ Hu, RB Vallee - Developmental cell, 2015 - cell.com
Dynein recruitment to the nuclear envelope is required for pre-mitotic nucleus-centrosome
interactions in nonneuronal cells and for apical nuclear migration in neural stem cells. In …
interactions in nonneuronal cells and for apical nuclear migration in neural stem cells. In …
The role of omega-3 fatty acids in preventing glucocorticoid-induced reduction in human hippocampal neurogenesis and increase in apoptosis
Glucocorticoids have been suggested to be involved in several neuropsychiatric disorders,
including depression. One of the possible mechanisms through which glucocorticoids …
including depression. One of the possible mechanisms through which glucocorticoids …
New insights into the intricacies of proneural gene regulation in the embryonic and adult cerebral cortex
Historically, the mammalian brain was thought to lack stem cells as no new neurons were
found to be made in adulthood. That dogma changed∼ 25 years ago with the identification …
found to be made in adulthood. That dogma changed∼ 25 years ago with the identification …
Rnd3 in cancer: a review of the evidence for tumor promoter or suppressor
L Paysan, L Piquet, F Saltel, V Moreau - Molecular Cancer Research, 2016 - AACR
Rho-GTPases are members of the Ras superfamily of small GTPases and are general
modulators of important cellular processes in tumor biology such as migration and …
modulators of important cellular processes in tumor biology such as migration and …
[HTML][HTML] Pathophysiological functions of rnd3/rhoe
W Jie, KC Andrade, X Lin, X Yang, X Yue… - Comprehensive …, 2015 - ncbi.nlm.nih.gov
Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small GTP-
binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound …
binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound …
[HTML][HTML] Binary fate choice between closely related interneuronal types is determined by a Fezf1-dependent postmitotic transcriptional switch
Many neuronal types occur as pairs that are similar in most respects but differ in a key
feature. In some pairs of retinal neurons, called paramorphic, one member responds to …
feature. In some pairs of retinal neurons, called paramorphic, one member responds to …
An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration
A transcriptional programme initiated by the proneural factors Neurog2 and Ascl1 controls
successive steps of neurogenesis in the embryonic cerebral cortex. Previous work has …
successive steps of neurogenesis in the embryonic cerebral cortex. Previous work has …
Cenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1
The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain,
including progenitor division and neuronal migration. Here we show that Cenpj, also known …
including progenitor division and neuronal migration. Here we show that Cenpj, also known …