Dendritic cells and the control of immunity

J Banchereau, RM Steinman - Nature, 1998 - nature.com
B and T lymphocytes are the mediators of immunity, but their function is under the control of
dendritic cells. Dendritic cells in the periphery capture and process antigens, express …

DNA vaccines: ready for prime time?

MA Kutzler, DB Weiner - Nature Reviews Genetics, 2008 - nature.com
Since the discovery, over a decade and a half ago, that genetically engineered DNA can be
delivered in vaccine form and elicit an immune response, there has been much progress in …

[HTML][HTML] Recent advances in cancer vaccines: challenges, achievements, and futuristic prospects

M Gupta, A Wahi, P Sharma, R Nagpal, N Raina… - Vaccines, 2022 - mdpi.com
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …

Engineered nucleic acids encoding a modified erythropoietin and their expression

JP Schrum, NB Afeyan, GJ Sieczkiewicz… - US Patent …, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

DNA vaccines: immunology, application, and optimization

S Gurunathan, DM Klinman… - Annual review of …, 2000 - annualreviews.org
The development and widespread use of vaccines against infectious agents have been a
great triumph of medical science. One reason for the success of currently available vaccines …

CCR7 as a therapeutic target in Cancer

A Salem, M Alotaibi, R Mroueh, HA Basheer… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The CCR7 chemokine axis is comprised of chemokine ligand 21 (CCL21) and chemokine
ligand 19 (CCL19) acting on chemokine receptor 7 (CCR7). This axis plays two important …

DNA vaccines: roles against diseases

KH Khan - Germs, 2013 - pmc.ncbi.nlm.nih.gov
Vaccination is the most successful application of immunological principles to human health.
Vaccine efficacy needs to be reviewed from time to time and its safety is an overriding …

DNA and RNA-based vaccines: principles, progress and prospects

WW Leitner, H Ying, NP Restifo - Vaccine, 1999 - Elsevier
DNA vaccines were introduced less than a decade ago but have already been applied to a
wide range of infectious and malignant diseases. Here we review the current understanding …

Cancer vaccines: between the idea and the reality

OJ Finn - Nature Reviews Immunology, 2003 - nature.com
Whether vaccines are designed to prepare the immune system for the encounter with a
pathogen or with cancer, certain common challenges need to be faced, such as what …