Cardiovascular disease is an important cause for morbidity and mortality worldwide.
Flavonoids, such as naringin, and naringenin are important natural phytochemicals in the …

A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …

Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

Substantial experimental evidences support the hypothesis that dietary flavonoid intake has
a favourable impact on cardiovascular diseases such as systemic, arterial hypertension and …

In addition to essential micronutrients such as vitamin C, citrus fruits represent a
considerably rich source of non-essential bioactive compounds, in particular flavanones …

Mitochondrial potassium channels have been described as important factors in cell pro-life
and death phenomena. The activation of mitochondrial potassium channels, such as ATP …

Sirtuin 1 (SIRT1) enzyme plays a pivotal role in the regulation of many physiological
functions. In particular, it is implicated in ageing‐related diseases, such as cardiac …

Mitochondrial dysfunction contributed greatly to myocardial ischemia-reperfusion (MI/R)-
induced cardiomyocyte apoptosis. Naringenin is a flavonoid exhibiting potential protective …

Flavonoids are found in natural health products and plant-based foods. The flavonoid
molecules contain a 15-carbon skeleton with the particular structural construction of …

Potassium channels are widely distributed integral proteins responsible for the effective and
selective transport of K+ ions through the biological membranes. According to the existing …