Haplotype‐association analysis
Association methods based on linkage disequilibrium (LD) offer a promising approach for
detecting genetic variations that are responsible for complex human diseases. Although …
detecting genetic variations that are responsible for complex human diseases. Although …
The haploty** problem: an overview of computational models and solutions
The investigation of genetic differences among humans has given evidence that mutations
in DNA sequences are responsible for some genetic diseases. The most common mutation …
in DNA sequences are responsible for some genetic diseases. The most common mutation …
Map** a New Spontaneous Preterm Birth Susceptibility Gene, IGF1R, Using Linkage, Haplotype Sharing, and Association Analysis
R Haataja, MK Karjalainen, A Luukkonen… - PLoS …, 2011 - journals.plos.org
Preterm birth is the major cause of neonatal death and serious morbidity. Most preterm births
are due to spontaneous onset of labor without a known cause or effective prevention. Both …
are due to spontaneous onset of labor without a known cause or effective prevention. Both …
Multipoint linkage analysis with many multiallelic or dense diallelic markers: Markov Chain–Monte Carlo provides practical approaches for genome scans on general …
Computations for genome scans need to adapt to the increasing use of dense diallelic
markers as well as of full-chromosome multipoint linkage analysis with either diallelic or …
markers as well as of full-chromosome multipoint linkage analysis with either diallelic or …
Efficient genome ancestry inference in complex pedigrees with inbreeding
Motivation: High-density SNP data of model animal resources provides opportunities for fine-
resolution genetic variation studies. These genetic resources are generated through a …
resolution genetic variation studies. These genetic resources are generated through a …
Genetic effects at pleiotropic loci are context-dependent with consequences for the maintenance of genetic variation in populations
Context-dependent genetic effects, including genotype-by-environment and genotype-by-
sex interactions, are a potential mechanism by which genetic variation of complex traits is …
sex interactions, are a potential mechanism by which genetic variation of complex traits is …
Change in maternal environment induced by cross-fostering alters genetic and epigenetic effects on complex traits in mice
The interaction between maternally provided environment and offspring genotype is a major
determinant of offspring development and fitness in many organisms. Recent research has …
determinant of offspring development and fitness in many organisms. Recent research has …
Association analysis of vitamin D-binding protein gene polymorphisms with variations of obesity-related traits in Caucasian nuclear families
H Jiang, DH **ong, YF Guo, H Shen, P **ao… - International journal of …, 2007 - nature.com
Background: Vitamin D-binding protein (DBP) gene is well known for its function on glucose
and vitamin D metabolism in human populations. Previous studies suggested that the in vivo …
and vitamin D metabolism in human populations. Previous studies suggested that the in vivo …
Pronounced inter-and intrachromosomal variation in linkage disequilibrium across the zebra finch genome
The extent of nonrandom association of alleles at two or more loci, termed linkage
disequilibrium (LD), can reveal much about population demography, selection, and …
disequilibrium (LD), can reveal much about population demography, selection, and …
Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females
J Zhao, DH **ong, Y Guo, TL Yang… - Human …, 2007 - academic.oup.com
BACKGROUND The insulin-like growth factor 1 (IGF1) gene, which plays a crucial role in
hypothalamic–pituitary–ovarian hormone-controlled metabolic processes, may influence the …
hypothalamic–pituitary–ovarian hormone-controlled metabolic processes, may influence the …