[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023‏ - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

2019 novel coronavirus (COVID-19) pandemic: built environment considerations to reduce transmission

L Dietz, PF Horve, DA Coil, M Fretz, JA Eisen… - Msystems, 2020‏ - Am Soc Microbiol
With the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that results in coronavirus disease 2019 (COVID-19), corporate entities, federal, state …

[HTML][HTML] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021‏ - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …

Impacts of biodiversity and biodiversity loss on zoonotic diseases

F Keesing, RS Ostfeld - Proceedings of the National …, 2021‏ - National Acad Sciences
Zoonotic diseases are infectious diseases of humans caused by pathogens that are shared
between humans and other vertebrate animals. Previously, pristine natural areas with high …

Origin and cross-species transmission of bat coronaviruses in China

A Latinne, B Hu, KJ Olival, G Zhu, L Zhang, H Li… - Nature …, 2020‏ - nature.com
Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of
Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of …

[HTML][HTML] The origin of COVID-19 and why it matters

DM Morens, JG Breman, CH Calisher… - The American journal …, 2020‏ - ncbi.nlm.nih.gov
The COVID-19 pandemic is among the deadliest infectious diseases to have emerged in
recent history. As with all past pandemics, the specific mechanism of its emergence in …

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

OA MacLean, S Lytras, S Weaver, JB Singer… - PLoS …, 2021‏ - journals.plos.org
Virus host shifts are generally associated with novel adaptations to exploit the cells of the
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …

The COVID-19 pandemic is intricately linked to biodiversity loss and ecosystem health

OK Lawler, HL Allan, PWJ Baxter… - The Lancet Planetary …, 2021‏ - thelancet.com
The ongoing COVID-19 pandemic, caused by zoonotic SARS-CoV-2, has important links to
biodiversity loss and ecosystem health. These links range from anthropogenic activities …

Evidence for SARS-CoV-2 infection of animal hosts

AS Abdel-Moneim, EM Abdelwhab - Pathogens, 2020‏ - mdpi.com
COVID-19 is the first known pandemic caused by a coronavirus, SARS-CoV-2, which is the
third virus in the family Coronaviridae to cause fatal infections in humans after SARS-CoV …

Host and viral traits predict zoonotic spillover from mammals

KJ Olival, PR Hosseini, C Zambrana-Torrelio, N Ross… - Nature, 2017‏ - nature.com
The majority of human emerging infectious diseases are zoonotic, with viruses that originate
in wild mammals of particular concern (for example, HIV, Ebola and SARS),,. Understanding …