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SARS-CoV-2 variant biology: immune escape, transmission and fitness
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …
SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …
mutations can affect viral properties such as infectivity and immune resistance. Although the …
2019 novel coronavirus (COVID-19) pandemic: built environment considerations to reduce transmission
With the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that results in coronavirus disease 2019 (COVID-19), corporate entities, federal, state …
that results in coronavirus disease 2019 (COVID-19), corporate entities, federal, state …
Impacts of biodiversity and biodiversity loss on zoonotic diseases
Zoonotic diseases are infectious diseases of humans caused by pathogens that are shared
between humans and other vertebrate animals. Previously, pristine natural areas with high …
between humans and other vertebrate animals. Previously, pristine natural areas with high …
Origin and cross-species transmission of bat coronaviruses in China
Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of
Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of …
Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of …
Zoonotic spillover: Understanding basic aspects for better prevention
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …
Most human infectious diseases (60-75%) are derived from pathogens that originally …
The origin of COVID-19 and why it matters
DM Morens, JG Breman, CH Calisher… - … American journal of …, 2020 - pmc.ncbi.nlm.nih.gov
The COVID-19 pandemic is among the deadliest infectious diseases to have emerged in
recent history. As with all past pandemics, the specific mechanism of its emergence in …
recent history. As with all past pandemics, the specific mechanism of its emergence in …
Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen
Virus host shifts are generally associated with novel adaptations to exploit the cells of the
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …
The COVID-19 pandemic is intricately linked to biodiversity loss and ecosystem health
The ongoing COVID-19 pandemic, caused by zoonotic SARS-CoV-2, has important links to
biodiversity loss and ecosystem health. These links range from anthropogenic activities …
biodiversity loss and ecosystem health. These links range from anthropogenic activities …