SARS-CoV-2 variant biology: immune escape, transmission and fitness

AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …

[HTML][HTML] Nanovaccines: a game changing approach in the fight against infectious diseases

MAH Abusalah, H Chopra, A Sharma… - Biomedicine & …, 2023 - Elsevier
The field of nanotechnology has revolutionised global attempts to prevent, treat, and
eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a …

SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021 - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …

2019 novel coronavirus (COVID-19) pandemic: built environment considerations to reduce transmission

L Dietz, PF Horve, DA Coil, M Fretz, JA Eisen… - Msystems, 2020 - journals.asm.org
With the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that results in coronavirus disease 2019 (COVID-19), corporate entities, federal, state …

Impacts of biodiversity and biodiversity loss on zoonotic diseases

F Keesing, RS Ostfeld - Proceedings of the National Academy of Sciences, 2021 - pnas.org
Zoonotic diseases are infectious diseases of humans caused by pathogens that are shared
between humans and other vertebrate animals. Previously, pristine natural areas with high …

Origin and cross-species transmission of bat coronaviruses in China

A Latinne, B Hu, KJ Olival, G Zhu, L Zhang, H Li… - Nature …, 2020 - nature.com
Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of
Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of …

Zoonotic spillover: Understanding basic aspects for better prevention

JH Ellwanger, JAB Chies - Genetics and molecular biology, 2021 - SciELO Brasil
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

The origin of COVID-19 and why it matters

DM Morens, JG Breman, CH Calisher… - … American journal of …, 2020 - pmc.ncbi.nlm.nih.gov
The COVID-19 pandemic is among the deadliest infectious diseases to have emerged in
recent history. As with all past pandemics, the specific mechanism of its emergence in …

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

OA MacLean, S Lytras, S Weaver, JB Singer… - PLoS …, 2021 - journals.plos.org
Virus host shifts are generally associated with novel adaptations to exploit the cells of the
new host species optimally. Surprisingly, Severe Acute Respiratory Syndrome Coronavirus …

The COVID-19 pandemic is intricately linked to biodiversity loss and ecosystem health

OK Lawler, HL Allan, PWJ Baxter… - The Lancet Planetary …, 2021 - thelancet.com
The ongoing COVID-19 pandemic, caused by zoonotic SARS-CoV-2, has important links to
biodiversity loss and ecosystem health. These links range from anthropogenic activities …