Microbiome as a biomarker and therapeutic target in pancreatic cancer

G Pourali, D Kazemi, AS Chadeganipour… - BMC microbiology, 2024 - Springer
Studying the effects of the microbiome on the development of different types of cancer has
recently received increasing research attention. In this context, the microbial content of …

Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for colorectal cancer

N Zafari, P Bathaei, M Velayati… - Computers in Biology …, 2023 - Elsevier
The considerable burden of colorectal cancer and the rising trend in young adults
emphasize the necessity of understanding its underlying mechanisms, providing new …

Lactobacillus plantarum J26 Alleviating Alcohol-Induced Liver Inflammation by Maintaining the Intestinal Barrier and Regulating MAPK Signaling Pathways

H Li, S Cheng, J Huo, K Dong, Y Ding, C Man, Y Zhang… - Nutrients, 2022 - mdpi.com
Alcoholic liver disease (ALD), as a global health problem, is mainly caused by liver
inflammation. Meanwhile, probiotics have been considered as a potential and promising …

[HTML][HTML] Alcohol and the brain–gut axis: the involvement of microglia and enteric glia in the process of neuro-enteric inflammation

MAS Khan, SL Chang - Cells, 2023 - mdpi.com
Binge or chronic alcohol consumption causes neuroinflammation and leads to alcohol use
disorder (AUD). AUD not only affects the central nervous system (CNS) but also leads to …

[HTML][HTML] The role of gut microbiota, exosomes, and their interaction in the pathogenesis of ALD

Z Cheng, L Yang, H Chu - Journal of Advanced Research, 2024 - Elsevier
Background The liver disorders caused by alcohol abuse are termed alcoholic-related liver
disease (ALD), including alcoholic steatosis, alcoholic steatohepatitis alcoholic hepatitis …

[HTML][HTML] The Protective Effect of Auricularia cornea var. Li. Polysaccharide on Alcoholic Liver Disease and Its Effect on Intestinal Microbiota

T Wang, Z Jia, C An, P Ren, Y Yang, W Wang, L Su - Molecules, 2023 - mdpi.com
This study's objective was to examine the protective effect and mechanism of a novel
polysaccharide (AYP) from Auricularia cornea var. Li. on alcoholic liver disease in mice. AYP …

[HTML][HTML] Immunological mechanisms in steatotic liver diseases: An overview and clinical perspectives

M Yan, S Man, L Ma, L Guo, L Huang… - Clinical and Molecular …, 2024 - pmc.ncbi.nlm.nih.gov
Steatotic liver diseases (SLD) are the principal worldwide cause of cirrhosis and end-stage
liver cancer, affecting nearly a quarter of the global population. SLD includes metabolic …

Can probiotic, prebiotic, and synbiotic supplementation modulate the gut-liver axis in type 2 diabetes? A narrative and systematic review of clinical trials

Y Al-Najjar, M Arabi, P Paul, A Chaari - Frontiers in Nutrition, 2022 - frontiersin.org
Background Type 2 diabetes, one of the most common noncommunicable diseases, is a
metabolic disorder that results in failed homeostatic control in several body systems …

Mechanism-based pharmacological management of chemotherapy-induced neuropathic pain from preclinical studies to clinical prospective: platinum-based drugs …

N Zafari, M Velayati, M Maftooh… - Current …, 2023 - benthamdirect.com
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a painful condition,
experienced by patients undergoing chemotherapy with some specific drugs, such as …

[HTML][HTML] Advancements in the alcohol-associated liver disease model

L Zhu, HD Li, JJ Xu, JJ Li, M Cheng, XM Meng… - Biomolecules, 2022 - mdpi.com
Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad
spectrum of liver damage. The presentation of ALD can include simple steatosis …