Extracellular vesicle analysis

A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …

Extracellular vesicles in kidney disease

C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Updating MISEV: Evolving the minimal requirements for studies of extracellular vesicles

KW Witwer, DCI Goberdhan, L O'Driscoll… - Journal of …, 2021 - Wiley Online Library
The minimal information for studies of extracellular vesicles (EVs, MISEV) is a field‐
consensus rigour initiative of the International Society for Extracellular Vesicles (ISEV). The …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

Extracellular vesicles as therapeutic resources in the clinical environment

J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …

[HTML][HTML] Exosomes in the diagnosis and treatment of renal cell cancer

S Boussios, P Devo, ICA Goodall, K Sirlantzis… - International Journal of …, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the most prevalent type of kidney cancer originating from
renal tubular epithelial cells, with clear cell RCC comprising approximately 80% of cases …

Urine biomarkers in bladder cancer—current status and future perspectives

M Maas, T Todenhöfer, PC Black - Nature Reviews Urology, 2023 - nature.com
Urine markers to detect bladder cancer have been the subject of research for decades. The
idea that urine—being in continuous contact with tumour tissue—should provide a vector of …

Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: A decade of research

M Ramirez-Garrastacho, C Bajo-Santos, A Line… - British journal of …, 2022 - nature.com
Prostate cancer is a global cancer burden and considerable effort has been made through
the years to identify biomarkers for the disease. Approximately a decade ago, the potential of …

Choline phosphate-grafted nanozymes as universal extracellular vesicle probes for bladder cancer detection

Q Li, S Zhan, X Yang, Z Zhang, N Sun, X Wang… - ACS …, 2024 - ACS Publications
Urinary extracellular vesicles (uEVs) are regarded as highly promising liquid-biopsy
biomarkers for the early diagnosis and prognosis of bladder cancer (BC). However …