Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing

DR Griffin, MM Archang, CH Kuan, WM Weaver… - Nature materials, 2021 - nature.com
Microporous annealed particle (MAP) scaffolds are flowable, in situ crosslinked,
microporous scaffolds composed of microgel building blocks and were previously shown to …

Hydrogels in the clinic

A Mandal, JR Clegg, AC Anselmo… - Bioengineering & …, 2020 - Wiley Online Library
Injectable hydrogels are one of the most widely investigated and versatile technologies for
drug delivery and tissue engineering applications. Hydrogels' versatility arises from their …

Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration

M Zhu, W Li, X Dong, X Yuan, AC Midgley… - Nature …, 2019 - nature.com
Implanted scaffolds with inductive niches can facilitate the recruitment and differentiation of
host cells, thereby enhancing endogenous tissue regeneration. Extracellular matrix (ECM) …

A review on the design of hydrogels with different stiffness and their effects on tissue repair

T Luo, B Tan, L Zhu, Y Wang, J Liao - Frontiers in bioengineering and …, 2022 - frontiersin.org
Tissue repair after trauma and infection has always been a difficult problem in regenerative
medicine. Hydrogels have become one of the most important scaffolds for tissue …

Advanced smart biomaterials and constructs for hard tissue engineering and regeneration

K Zhang, S Wang, C Zhou, L Cheng, X Gao, X **e… - Bone research, 2018 - nature.com
Hard tissue repair and regeneration cost hundreds of billions of dollars annually worldwide,
and the need has substantially increased as the population has aged. Hard tissues include …