Coordination compounds in cancer: Past, present and perspectives

F Trudu, F Amato, P Vaňhara, T Pivetta… - Journal of applied …, 2015 - Elsevier
Metal-based coordination compounds have been used throughout the history of human
medicine to treat various diseases, including cancer. Since the discovery of cisplatin in …

Controlled self-assembly, isomerism, and guest uptake/release of charge-reversible lanthanide–organic octahedral cages

LP Zhou, XS Feng, SJ Hu, QF Sun - Journal of the American …, 2023 - ACS Publications
Charge plays a crucial role in the function of molecular and supramolecular systems, but
coordination hosts capable of orthogonal charge regulation remain elusive so far. In this …

A brief overview of metal complexes as nuclear imaging agents

DS MacPherson, K Fung, BE Cook… - Dalton …, 2019 - pubs.rsc.org
Metallic radionuclides have been instrumental in the field of nuclear imaging for over half a
century. While recent years have played witness to a dramatic rise in the use of radiometals …

[HTML][HTML] Effect of morphology and (Sn, Cr) do** on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures

R Pilliadugula, J Haribabu, MKM Subarkhan… - Journal of science …, 2021 - Elsevier
GaOOH powders of submicron dimensions were synthesized through a simple, surfactant-
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …

Evaluation of in vitro distribution and plasma protein binding of selected antiviral drugs (favipiravir, molnupiravir and imatinib) against SARS-CoV-2

O Dömötör, ÉA Enyedy - International Journal of Molecular Sciences, 2023 - mdpi.com
There are a number of uncertainties regarding plasma protein binding and blood distribution
of the active drugs favipiravir (FAVI), molnupiravir (MOLNU) and imatinib (IMA), which were …

[HTML][HTML] Solution chemical properties and anticancer potential of 8-hydroxyquinoline hydrazones and their oxidovanadium (IV) complexes

N Ribeiro, I Bulut, V Pósa, B Sergi, G Sciortino… - Journal of Inorganic …, 2022 - Elsevier
We report the synthesis and characterization of a family of benzohydrazones (L n, n= 1–6)
derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing different …

Metal coordination and biological screening of a Schiff Base derived from 8-hydroxyquinoline and benzothiazole

N Ribeiro, PF Farinha, JO Pinho, H Luiz, JP Mészáros… - Pharmaceutics, 2022 - mdpi.com
Designing new metallodrugs for anticancer therapy is a driving force in the scientific
community. Aiming to contribute to this field, we hereby report the development of a Schiff …

Antitumor pentamethylcyclopentadienyl rhodium complexes of maltol and allomaltol: Synthesis, solution speciation and bioactivity

O Dömötör, S Aicher, M Schmidlehner… - Journal of Inorganic …, 2014 - Elsevier
The reaction of the dimer [Rh III (pentamethylcyclopentadienyl)(μ-Cl) Cl] 2 ([Rh III (Cp*)(μ-Cl)
Cl] 2) with the hydroxypyrone ligands maltol and allomaltol affords complexes of the general …

Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases

VFS Pape, NV May, GT Gál, I Szatmári, F Szeri… - Dalton …, 2018 - pubs.rsc.org
The anticancer activity of 8-hydroxyquinolines relies on complex formation with redox active
copper and iron ions. Here we employ UV-visible spectrophotometry and EPR spectroscopy …

Gallium (III) complex with cloxyquin ligands induces ferroptosis in cancer cells and is a potent agent against both differentiated and tumorigenic cancer stem …

M Hreusova, V Novohradsky, L Markova… - Bioinorganic …, 2022 - Wiley Online Library
In this work, gallium (III) complex with cloxyquin (5‐chloro‐8‐quinolinol, HClQ) ligands is
shown to effectively inhibit proliferation of rhabdomyosarcoma cells, the frequent …