Rebuilding the lid region from conformational and dynamic features to engineering applications of lipase in foods: Current status and future prospects

G Chen, IM Khan, W He, Y Li, P **… - … Reviews in Food …, 2022 - Wiley Online Library
The applications of lipases in esterification, amidation, and transesterification have
broadened their potential in the production of fine compounds with high cumulative values …

Discovery and mechanism-guided engineering of BHET hydrolases for improved PET recycling and upcycling

A Li, Y Sheng, H Cui, M Wang, L Wu, Y Song… - Nature …, 2023 - nature.com
Although considerable research achievements have been made to address the plastic crisis
using enzymes, their applications are limited due to incomplete degradation and low …

Enzyme engineering for functional lipids synthesis: recent advance and perspective

A Guan, Y Hou, R Yang, J Qin - Bioresources and Bioprocessing, 2024 - Springer
Functional lipids, primarily derived through the modification of natural lipids by various
processes, are widely acknowledged for their potential to impart health benefits. In contrast …

Immobilization of lipases via interfacial activation on hydrophobic supports: Production of biocatalysts libraries by altering the immobilization conditions

S Arana-Peña, NS Rios, D Carballares… - Catalysis Today, 2021 - Elsevier
Lipases A and B from Candida antarctica (CALA, CALB), and those from Candida rugosa
(CRL) and Rhizomucor miehei (RML) have been immobilized on octyl agarose beads under …

A mutant T1 lipase homology modeling, and its molecular docking and molecular dynamics simulation with fatty acids

X Qin, J Zhong, Y Wang - Journal of biotechnology, 2021 - Elsevier
A thermostable T1 lipase from Geobacillus zalihae exhibits broad substrate specificity and
good potential application in fats and oils. However, structural insight into the enzyme …

Structure-Guided Rational Design of a Mono- and Diacylglycerol Lipase from Aspergillus oryzae: A Single Residue Mutant Increases the Hydrolysis Ability

D Lan, G Zhao, N Holzmann, S Yuan… - Journal of Agricultural …, 2021 - ACS Publications
Engineering of enzymes on the basis of protein structures are rational and efficient
approaches to acquire biocatalysts of desired performances. In this study, we focused on a …

Genetically modified food enzymes: a review

Y Zhang, T Geary, BK Simpson - Current Opinion in Food Science, 2019 - Elsevier
Highlights•Food enzyme modification is developed by advanced genetic techniques.•
Genetically modified food enzymes can exhibit improved catalytic efficiency, stability …

Altering the Regioselectivity of T1 Lipase from Geobacillus zalihae toward sn-3 Acylglycerol Using a Rational Design Approach

SH Albayati, M Masomian, SNH Ishak, ATC Leow… - Catalysts, 2023 - mdpi.com
The regioselectivity characteristic of lipases facilitate a wide range of novel molecule unit
constructions and fat modifications. Lipases can be categorized as sn-1, 3, sn-2, and …

Genetically modified crops and sustainable development: navigating challenges and opportunities

R Sandhu, N Chaudhary, R Shams… - Food Science and …, 2024 - Springer
Abstract The dominance of Genetically Modified (GM) crops in global agriculture is
underscored by the production quantities of GM Maize and GM soybean. This review …

Role of enzymatic bioprocesses for the production of functional food and nutraceuticals

R Chourasia, LC Phukon, SP Singh, AK Rai… - Biomass, biofuels …, 2020 - Elsevier
Green technologies such as enzyme bioprocess tend to satisfy the ever-growing demand of
functional food in the food industry. Enzymes such as proteases, lipases, carbohydrase …