Structure and Function of Dynein's Non-Catalytic Subunits

L Rao, A Gennerich - Cells, 2024 - mdpi.com
Dynein, an ancient microtubule-based motor protein, performs diverse cellular functions in
nearly all eukaryotic cells, with the exception of land plants. It has evolved into three …

Passage of the HIV capsid cracks the nuclear pore

JP Kreysing, M Heidari, V Zila, S Cruz-Leon… - Cell, 2025 - cell.com
Upon infection, human immunodeficiency virus type 1 (HIV-1) releases its cone-shaped
capsid into the cytoplasm of infected T cells and macrophages. The capsid enters the …

[HTML][HTML] TRIM Proteins and Antiviral Microtubule Reorganization: A Novel Component in Innate Immune Responses?

C Vadon, MM Magiera, A Cimarelli - Viruses, 2024 - mdpi.com
TRIM proteins are a family of innate immune factors that play diverse roles in innate
immunity and protect the cell against viral and bacterial aggression. As part of this special …

[HTML][HTML] Expanding Insights: Harnessing Expansion Microscopy for Super-Resolution Analysis of HIV-1–Cell Interactions

A Petrich, GM Hwang, L La Rocca, M Hassan… - Viruses, 2024 - mdpi.com
Expansion microscopy has recently emerged as an alternative technique for achieving high-
resolution imaging of biological structures. Improvements in resolution are achieved by …

The intracellular bacterium Orientia tsutsugamushi hijacks the adaptor protein BICD2 for dynein-based motility

G Manigrasso, K Saharat, C Kullapanich, J Boulanger… - bioRxiv, 2024 - biorxiv.org
The intracellular bacterium Orientia tsutsugamushi relies on the microtubule cytoskeleton
and the motor protein dynein to traffic to the perinuclear region within infected cells …