An update on the epidemiology of type 2 diabetes: a global perspective

MG Tinajero, VS Malik - Endocrinology and Metabolism Clinics, 2021 - endo.theclinics.com
Type 2 diabetes (T2D) is a chronic health condition that has reached alarming rates across
the globe. A little more than 2 decades ago, the International Diabetes Federation (IDF) …

Severe malnutrition or famine exposure in childhood and cardiometabolic non-communicable disease later in life: a systematic review

K Grey, GB Gonzales, M Abera, N Lelijveld… - BMJ global …, 2021 - gh.bmj.com
Introduction Child malnutrition (undernutrition) and adult non-communicable diseases
(NCDs) are major global public health problems. While convincing evidence links prenatal …

Cohort profile: the Dutch famine birth cohort (DFBC)—a prospective birth cohort study in the Netherlands

LS Bleker, SR de Rooij, RC Painter, ACJ Ravelli… - BMJ open, 2021 - bmjopen.bmj.com
Purpose The Dutch famine birth cohort study was set up to investigate the effects of acute
maternal undernutrition of the 1944–1945 Dutch famine during the specific stages of …

Health consequences of obesity and projected future obesity health burden in China

X Sun, AF Yan, Z Shi, B Zhao, N Yan, K Li, L Gao… - …, 2022 - Wiley Online Library
Objective This study examined the effects of overweight/obesity on mortality and morbidity
outcomes and the disparities, time trends, and projected future obesity health burden in …

Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine

P Zimmet, Z Shi, A El-Osta, L Ji - Nature Reviews Endocrinology, 2018 - nature.com
The gene–environment interactions resulting from famine and the subsequent increased
intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current …

Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET …

LW Chen, AM Aubert, N Shivappa, JY Bernard… - BMC medicine, 2021 - Springer
Background Mounting evidence suggests that maternal diet influences pregnancy and birth
outcomes, but its contribution to the global epidemic of childhood obesity has not as yet …

Epigenetics in obesity and diabetes mellitus: new insights

R Suárez, SP Chapela, L Álvarez-Córdova… - Nutrients, 2023 - mdpi.com
A long-term complication of obesity is the development of type 2 diabetes (T2D). Patients
with T2D have been described as having epigenetic modifications. Epigenetics is the post …

Weight gain after HIV therapy initiation: pathophysiology and implications

NC Chandiwana, MJ Siedner… - The Journal of …, 2024 - academic.oup.com
Rapid advances in the potency, safety, and availability of modern HIV antiretroviral therapy
(ART) have yielded a near-normal life expectancy for most people living with HIV (PLWH) …

Developmental origins of type 2 diabetes: Focus on epigenetics

A Vaiserman, O Lushchak - Ageing Research Reviews, 2019 - Elsevier
Traditionally, genetics and lifestyle are considered as main determinants of aging-
associated pathological conditions. Accumulating evidence, however, suggests that risk of …

Famine and trajectories of body mass index, waist circumference, and blood pressure in two generations: results from the CHNS from 1993–2015

J Li, Q Yang, R An, HD Sesso, VW Zhong… - …, 2022 - Am Heart Assoc
Background: Early-life exposures play key roles in the development of metabolic diseases.
Whether such effects exist beyond one generation remains unclear. This study aimed to …