Pyroptosis: mechanisms and diseases
P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …
innate immunity and disease. The research scope of pyroptosis has expanded with the …
ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities
Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
coronavirus 19 disease (COVID-19) which presents a large spectrum of manifestations with …
coronavirus 19 disease (COVID-19) which presents a large spectrum of manifestations with …
The protein expression profile of ACE2 in human tissues
The novel SARS‐coronavirus 2 (SARS‐CoV‐2) poses a global challenge on healthcare and
society. For understanding the susceptibility for SARS‐CoV‐2 infection, the cell type‐specific …
society. For understanding the susceptibility for SARS‐CoV‐2 infection, the cell type‐specific …
The GeneCards suite: from gene data mining to disease genome sequence analyses
G Stelzer, N Rosen, I Plaschkes… - Current protocols in …, 2016 - Wiley Online Library
GeneCards, the human gene compendium, enables researchers to effectively navigate and
inter‐relate the wide universe of human genes, diseases, variants, proteins, cells, and …
inter‐relate the wide universe of human genes, diseases, variants, proteins, cells, and …
Decoding myofibroblast origins in human kidney fibrosis
Kidney fibrosis is the hallmark of chronic kidney disease progression; however, at present
no antifibrotic therapies exist,–. The origin, functional heterogeneity and regulation of scar …
no antifibrotic therapies exist,–. The origin, functional heterogeneity and regulation of scar …
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
Global classification of the human proteins with regards to spatial expression patterns
across organs and tissues is important for studies of human biology and disease. Here, we …
across organs and tissues is important for studies of human biology and disease. Here, we …
Gasdermins: effectors of pyroptosis
SB Kovacs, EA Miao - Trends in cell biology, 2017 - cell.com
Pyroptosis is a form of lytic programmed cell death initiated by inflammasomes, which detect
cytosolic contamination or perturbation. This drives activation of caspase-1 or caspase …
cytosolic contamination or perturbation. This drives activation of caspase-1 or caspase …
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …
DGIdb 3.0: a redesign and expansion of the drug–gene interaction database
The drug–gene interaction database (DGIdb, www. dgidb. org) consolidates, organizes and
presents drug–gene interactions and gene druggability information from papers, databases …
presents drug–gene interactions and gene druggability information from papers, databases …
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA …
Background Tumor-infiltrating immune cells have been linked to prognosis and response to
immunotherapy; however, the levels of distinct immune cell subsets and the signals that …
immunotherapy; however, the levels of distinct immune cell subsets and the signals that …