Studying the coevolutionary dynamics between bacteria and the bacteriophage viruses that
infect them is critical to understanding both microbial diversity and ecosystem functioning …

Phage therapy—application of bacteria-specific viruses to reduce densities of pathogenic or
nuisance bacteria—is a two-step process involving phage penetration to target bacteria …

For ideal gasses, the likelihood of collision of two molecules is a function of concentrations
as well as environmental factors such as temperature. This too is the case for particles …

The complete genome sequences of over 220 mycobacteriophages reveal them to be highly
diverse, with numerous types sharing little or no nucleotide sequence identity with each …

Many studies on phage biology are based on isolation methods that may inadvertently
select for narrow-host-range phages. Consequently, broad-host-range phages, whose …

Background The appearance of plaques on a bacterial lawn is one of the enduring
imageries in modern day biology. The seeming simplicity of a plaque has invited many …

The biological functions of bacteriophage virions come down to the solution of three basic
problems: to provide protection of viral nucleic acid from the factors of extracellular …

Background Members of the genus Klebsiella are among the leading microbial pathogens
associated with nosocomial infection. The increased incidence of antimicrobial resistance in …

Background Enterococcus faecium is one of the members of ESKAPE pathogens. Due to its
resistance to antimicrobial agents, treating this bacterium has become challenging. The …

Urinary tract infections (UTIs) caused by resistant Klebsiella pneumoniae can lead to severe
clinical complications and even death. An alternative treatment option for infected patients is …