Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR‐Preserved

AJS Coats, J Butler, H Tsutsui… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Frailty is a severe, common co‐morbidity associated with heart failure (HF) with
preserved ejection fraction (HFpEF). The impact of frailty on HFpEF outcomes may affect …

A patient with heart failure, who is frail: How does this affect therapeutic decisions?

M Wleklik, Q Denfeld, M Czapla… - Cardiology …, 2023 - journals.viamedica.pl
Patients with heart failure (HF) are heterogeneous, not only related to comorbidities but also
in the presentation of frailty syndrome. Frailty syndrome also affects patients with HF across …

Association between frailty and adverse outcomes after cardiac resynchronization therapy: a systematic review and meta-analysis

X Li, F Fang - European Geriatric Medicine, 2024 - Springer
Aim To synthesize evidence, using data from published studies, on the association of frailty
with the outcomes after cardiac resynchronization therapy (CRT). Methods The systematic …

Frailty status modifies the efficacy of ICD therapy for primary prevention among patients with HF

MW Segar, N Keshvani, S Singh, L Patel, S Parsa… - Heart Failure, 2024 - jacc.org
Background Implantable cardioverter-defibrillator (ICD) therapy is recommended to reduce
mortality risk in patients with heart failure with reduced ejection fraction (HFrEF). Frailty is …

Mortality from all-cause and cause-specific in the elderly: joint implications of anemia and frailty

HR Zhang, X Wei, XT Chen, XD Sun - Archives of Gerontology and …, 2023 - Elsevier
Background Anemia is prevalent among older adults, and it contributes to the incidence of
frailty. In turn, the frail elderly may be deficient in nutrients, including iron, vitamin B-12, and …

Multispecialty multidisciplinary input into comorbidities along with treatment optimisation in heart failure reduces hospitalisation and clinic attendance

H Essa, L Walker, K Mohee, C Oguguo, H Douglas… - Open …, 2022 - openheart.bmj.com
Aims Heart failure (HF) is associated with comorbidities which independently influence
treatment response and outcomes. This retrospective observational study (January 2020 …

Telehealth‐aided outpatient management of acute heart failure in a specialist virtual ward compared with standard care

R Sankaranarayanan, D Rasoul, N Murphy… - ESC Heart …, 2024 - Wiley Online Library
Aims The aim of this propensity score matched cohort study was to assess the outcomes of
telehealth‐guided outpatient management of acute heart failure (HF) in our virtual ward …

Prognostic impact of frailty based on a comprehensive frailty assessment in patients with heart failure

T Hamada, T Kubo, K Kawai, Y Nakaoka… - ESC Heart …, 2024 - Wiley Online Library
Aims This study aimed to evaluate the impact of frailty and living function domains based on
the Kihon Checklist (KCL), a questionnaire for a comprehensive frailty assessment, on …

Physical frailty, genetic predisposition, and incident heart failure

Q Shi, J Huang, J Wan, Z Zhong, Y Sun, Y Zhou, J Li… - JACC: Asia, 2024 - jacc.org
Background There is growing interest in the intersection of frailty and heart failure (HF);
however, large-sample longitudinal studies in the general population are lacking. Objectives …

The Association Between Beta-blocker and Renin–Angiotensin System Inhibitor Use After Heart Failure With Reduced Ejection Fraction Hospitalization and Outcomes …

L Gilstrap, N Solomon, K Chiswell, AJ O'MALLEY… - Journal of Cardiac …, 2023 - Elsevier
Introduction Beta-blockers (BB) and renin–angiotensin system inhibitors (RASi) are
foundational for the treatment of heart failure with reduced ejection fraction (HFrEF) …