Genetic predisposition to obesity presents a paradox: how do genetic variants with a
detrimental impact on human health persist through evolutionary time? Numerous …

There is little information on inbreeding during the critical early years of human existence.
However, given the small founding group sizes and restricted mate choices it seems …

IntroductIon reconceiving Middle Eastern Manhood this book is a tribute to Middle Eastern
men such as Hamza, my driver in Lebanon, whose stories never make it to the front pages of …

The human genome is characterised by many runs of homozygous genotypes, where
identical haplotypes were inherited from each parent. The length of each run is determined …

Marriage between close biological relatives is generally regarded with suspicion and
distaste within Western society, reflecting historical and religious prejudice. By comparison …

Consanguineous marriage is a major feature of family systems in south-west Asia. The aim
of the present study was to determine the current prevalence and patterns of consanguinity …

Purpose: To estimate the prevalence of sickle cell disorders and beta thalassemia, with their
regional distribution, in the adult population screened as part of the Saudi Premarital …

Consanguineous marriage is customary in many societies, but leads to an increased birth
prevalence of infants with severe recessive disorders. It is therefore often proposed that …

Background Consanguinity is the close union, sexual relationship or marriage between
persons who have common biological ancestors usually up to about 2nd cousins. Contrary …

The objective of this document is to provide recommendations for genetic counseling and
screening for consanguineous couples (related as second cousins or closer) and their …