An understanding of the diversity of cortical GABAergic interneurons is critical to understand
the function of the cerebral cortex. Recent data suggest that neurons expressing three …

▪ Abstract We explore the extent to which neocortical circuits generalize, ie, to what extent
can neocortical neurons and the circuits they form be considered as canonical? We find that …

We present a first-draft digital reconstruction of the microcircuitry of somatosensory cortex of
juvenile rat. The reconstruction uses cellular and synaptic organizing principles to …

Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no
external sound is present. Most but not all cases are associated with hearing loss induced …

Inhibitory interneurons are critical to sensory transformations, plasticity and synchronous
activity in the neocortex,. There are many types of inhibitory neurons, but their synaptic …

The quantal release of glutamate depends on its transport into synaptic vesicles. Recent
work has shown that a protein previously implicated in the uptake of inorganic phosphate …

Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Attention is critical to high-level cognition and attention deficits are a hallmark of neurologic
and neuropsychiatric disorders. Although years of research indicates that distinct …

We developed a quantitative description of the circuits formed in cat area 17 by estimating
the “weight” of the projections between different neuronal types. To achieve this, we made …

Sensory stimuli reach the brain via the thalamocortical projection, a group of axons thought
to be among the most powerful in the neocortex. Surprisingly, these axons account for …