RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

The use of implantable medical devices is a common and indispensable part of medical
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …

Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …

The implants are increasingly being a part of modern medicine in various surgical
procedures for functional or cosmetic purposes. The progressive use of implants is …

Gene therapy for neurological disorders has attracted significant interest as a way to reverse
or stop various disease pathologies. Typical gene therapies involving the central and …

Therapies capable of decelerating, or perhaps even halting, neurodegeneration in
Parkinson's disease (PD) remain elusive. Clinical trials of PD gene therapy testing the …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in the adult
population and it carries a dismal prognosis. Inefficient drug delivery across the blood brain …

Major advancements in targeted gene therapy have opened up avenues for the treatment of
major neurological disorders through a range of versatile modalities varying from expression …

Gene therapy holds promise for the treatment of many pathologies of the central nervous
system (CNS), including brain tumors and neurodegenerative diseases. However, the …

Efficient methods for cell line transfection are well described, but, for primary neurons, a high-
yield method different from those relying on viral vectors is lacking. Viral transfection has …