Benzothiazole (BTA) and its derivatives are the most important heterocyclic compounds,
which are common and integral feature of a variety of natural products and pharmaceutical …

The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …

In recent years heterocyclic compounds analogues and derivatives have attracted wide
attention due to their useful biological and pharmacological properties. Benzothiazole is …

Type 2 diabetes mellitus (T2D) is a metabolic disorder that knows no boundaries and is
spread across the globe. It is one of the most widely spread metabolic disorder, which has …

Diabetes mellitus is the most serious and prevalent metabolic disorders worldwide,
complications of which can decrease significantly the quality of life and contribute to …

Obesity and metabolic syndrome represent major public health problems, and are the
biggest preventable causes of death worldwide. Obesity is the leading risk factor for type 2 …

A novel series of substituted (E)-3-(Benzo [d] thiazol-2-ylamino) phenylprop-2-en-1-onewere
synthesized starting from 2-aminobenzothiazole and 1-aryl-3, 3-bis-(methylsulfanyl)-2 …

Background: Protein tyrosine phosphatase 1B (PTP1B) is an important therapeutic target for
type II diabetes and obesity because of its pivotal role as a negative modulator in both …

As a disease closely related to the metabolic syndrome, diabetes has become a public
health issue that severely affects many people's quality of life. The search for novel anti …

A small series of thiazolidine‐2, 4‐dione and barbituric acid derivatives 1–4 was prepared
using a short synthetic route, and all compounds were characterized by elemental analysis …