Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021 - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

[HTML][HTML] Automated liquid-handling operations for robust, resilient, and efficient bio-based laboratory practices

MA Torres-Acosta, GJ Lye, D Dikicioglu - Biochemical Engineering Journal, 2022 - Elsevier
Increase in the adoption of liquid handling devices (LHD) can facilitate experimental
activities. Initially adopted by businesses and industry-based laboratories, the practice has …

PlasmidMaker is a versatile, automated, and high throughput end-to-end platform for plasmid construction

B Enghiad, P Xue, N Singh, AG Boob, C Shi… - Nature …, 2022 - nature.com
Plasmids are used extensively in basic and applied biology. However, design and
construction of plasmids, specifically the ones carrying complex genetic information, remains …

Standardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiae and Emerging Yeast Species

K Malcı, E Watts, TM Roberts, JY Auxillos… - ACS synthetic …, 2022 - ACS Publications
As redesigning organisms using engineering principles is one of the purposes of synthetic
biology (SynBio), the standardization of experimental methods and DNA parts is becoming …

Building a biofoundry

MB Holowko, EK Frow, JC Reid, M Rourke… - Synthetic …, 2021 - academic.oup.com
A biofoundry provides automation and analytics infrastructure to support the engineering of
biological systems. It allows scientists to perform synthetic biology and aligned …

Accelerating strain engineering in biofuel research via build and test automation of synthetic biology

J Zhang, Y Chen, L Fu, E Guo, B Wang, L Dai… - Current Opinion in …, 2021 - Elsevier
Highlights•The lack of predictive modeling limits biosystems design for biofuel production.•
Automation in build and test accelerates strain engineering for biofuel research.•Microplates …

Synthetic biology and bioelectrochemical tools for electrogenetic system engineering

JM Lawrence, Y Yin, P Bombelli, A Scarampi… - Science …, 2022 - science.org
Synthetic biology research and its industrial applications rely on deterministic
spatiotemporal control of gene expression. Recently, electrochemical control of gene …

Biological materials: the next frontier for cell-free synthetic biology

RJR Kelwick, AJ Webb, PS Freemont - Frontiers in Bioengineering …, 2020 - frontiersin.org
Advancements in cell-free synthetic biology are enabling innovations in sustainable
biomanufacturing, that may ultimately shift the global manufacturing paradigm toward …

Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly

R Young, M Haines, M Storch, PS Freemont - Metabolic Engineering, 2021 - Elsevier
Synthetic Biology is a rapidly growing interdisciplinary field that is primarily built upon
foundational advances in molecular biology combined with engineering design principles …

Physical laboratory automation in synthetic biology

A Stephenson, L Lastra, B Nguyen, YJ Chen… - ACS Synthetic …, 2023 - ACS Publications
Synthetic Biology has overcome many of the early challenges facing the field and is entering
a systems era characterized by adoption of Design-Build-Test-Learn (DBTL) approaches …