Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …

Mitochondrial dynamics shape the mitochondrial network and contribute to mitochondrial
function and quality control. Mitochondrial fusion and division are integrated into diverse …

Mitophagy is activated by a number of stimuli, including hypoxia, energy stress, and
increased oxidative phosphorylation activity. Mitophagy is associated with oxidative stress …

Aging is a prominent risk factor for neurodegenerative disorders (NDDs); however, the
molecular mechanisms rendering the aged brain particularly susceptible to …

Aging is associated with multiple human pathologies. In the past few years mitochondrial
homeostasis has been well correlated with age-related disorders and longevity …

The expected increase in prevalence of Parkinson's disease (PD) as the most common
neurodegenerative movement disorder over the next years underscores the need for a …

Abstract Miro (mitochondrial Rho GTPases) a mitochondrial outer membrane protein, plays
a vital role in the microtubule-based mitochondrial axonal transport, mitochondrial dynamics …

It is now recognized that tumors are not merely masses of transformed cells but are
intricately interconnected with healthy cells in the tumor microenvironment (TME), forming …