The role of hepatokines in NAFLD
Non-alcoholic fatty liver disease (NAFLD) is not only a consequence of insulin resistance,
but it is also an important cause of insulin resistance and major non-communicable diseases …
but it is also an important cause of insulin resistance and major non-communicable diseases …
Metabolic syndrome
The metabolic syndrome (MetS) is a multiplex modifiable risk factor for cardiovascular
disease, type 2 diabetes mellitus and other health outcomes, and is a major challenge to …
disease, type 2 diabetes mellitus and other health outcomes, and is a major challenge to …
Inflammation–nature's way to efficiently respond to all types of challenges: implications for understanding and managing “the epidemic” of chronic diseases
Siloed or singular system approach to disease management is common practice,
develo** out of traditional medical school education. Textbooks of medicine describe a …
develo** out of traditional medical school education. Textbooks of medicine describe a …
Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
RCR Meex, MJ Watt - Nature Reviews Endocrinology, 2017 - nature.com
Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …
is the most common form of liver disease and is present in up to∼ 70% of individuals who …
Cytokines and abnormal glucose and lipid metabolism
J Shi, J Fan, Q Su, Z Yang - Frontiers in endocrinology, 2019 - frontiersin.org
Clear evidence indicates that cytokines, for instance, adipokines, hepatokines, inflammatory
cytokines, myokines, and osteokines, contribute substantially to the development of …
cytokines, myokines, and osteokines, contribute substantially to the development of …
The role of exercise in the interplay between myokines, hepatokines, osteokines, adipokines, and modulation of inflammation for energy substrate redistribution and …
Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
[HTML][HTML] Hepatokines and metabolism: Deciphering communication from the liver
SO Jensen-Cody, MJ Potthoff - Molecular metabolism, 2021 - Elsevier
Background The liver is a key regulator of systemic energy homeostasis and can sense and
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …
respond to nutrient excess and deficiency through crosstalk with multiple tissues. Regulation …
The impact of insulin resistance on the kidney and vasculature
F Artunc, E Schleicher, C Weigert, A Fritsche… - Nature Reviews …, 2016 - nature.com
Insulin resistance is a systemic disorder that affects many organs and insulin-regulated
pathways. The disorder is characterized by a reduced action of insulin despite increased …
pathways. The disorder is characterized by a reduced action of insulin despite increased …
Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease
Non-alcoholic fatty liver disease is marked by hepatic fat accumulation not due to alcohol
abuse. Several studies have demonstrated that NAFLD is associated with insulin resistance …
abuse. Several studies have demonstrated that NAFLD is associated with insulin resistance …
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach
Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological
pathways and help to identify individuals at risk for disease. We prospectively investigated …
pathways and help to identify individuals at risk for disease. We prospectively investigated …