Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass and increased risk of fragility fractures. Twin and family studies have …

Osteoporosis, or bone loss, is a progressive, systemic skeletal disease that affects millions of
people worldwide. Osteoporosis is generally age related, and it is underdiagnosed because …

Osteoporosis is the most common multifactorial metabolic bone disorder worldwide with a
strong genetic component. In this review, the evidence for a genetic contribution to …

Background: The gene encoding oestrogen receptor α (ESR1) appears to regulate bone
mineral density (BMD) and other determinants of osteoporotic fracture risk. Objective: To …

This review summarizes comprehensively the most important and representative molecular
genetics studies of gene identification for osteoporosis published up to the end of December …

Osteoporosis is a common disease with a strong genetic component characterised by
reduced bone mass and an increased risk of fragility fractures. Twin and family studies have …

Obesity is a multifactorial disorder with a complex phenotype. It is a significant risk factor for
diabetes and hypertension. We assessed obesity-related traits in a large cohort of twins and …

The pathogenesis of osteoporosis involves both genetic and environmental factors. On the
basis of linkage data suggesting gene effects on bone density at chromosome 14q and data …

Osteoporosis, which is characterised by reduced bone mineral density (BMD) and an
increased risk of fragility fractures, is the result of a complex interaction between …