Toll‐like receptor polymorphism in host immune response to infectious diseases: A review

S Mukherjee, S Huda… - Scandinavian journal of …, 2019‏ - Wiley Online Library
Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …

Variation matters: TLR structure and species-specific pathogen recognition

D Werling, OC Jann, V Offord, EJ Glass, TJ Coffey - Trends in immunology, 2009‏ - cell.com
Toll-like receptors (TLRs) are a family of pattern recognition receptors that are an important
link between innate and adaptive immunity. Many vaccines incorporate ligands for TLRs as …

Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

H Areal, J Abrantes, PJ Esteves - BMC evolutionary biology, 2011‏ - Springer
Abstract Background Toll-like receptors (TLRs) are a major class of pattern recognition
receptors (PRRs) expressed in the cell surface or membrane compartments of immune and …

Adjuvants and delivery systems in veterinary vaccinology: current state and future developments

PMH Heegaard, L Dedieu, N Johnson, MF Le Potier… - Archives of …, 2011‏ - Springer
Modern adjuvants should induce strong and balanced immune responses, and it is often
desirable to induce specific types of immunity. As an example, efficient Th1-immunity …

Applications of nanovaccines for disease prevention in cattle

TW Maina, EA Grego, PM Boggiatto… - … in bioengineering and …, 2020‏ - frontiersin.org
Vaccines are one of the most important tools available to prevent and reduce the incidence
of infectious diseases in cattle. Despite their availability and widespread use to combat …

Porcine Toll-like receptors: the front line of pathogen monitoring and possible implications for disease resistance

H Uenishi, H Shinkai - Developmental & Comparative Immunology, 2009‏ - Elsevier
Toll-like receptors (TLRs) are the most famous pattern-recognition receptors (PRRs); they
monitor pathogen-associated molecular patterns and play a critical role in activation of the …

TLR8: an innate immune receptor in brain, neurons and axons

Y Ma, RL Haynes, RL Sidman, T Vartanian - Cell Cycle, 2007‏ - Taylor & Francis
Toll-like receptors (TLRs) play essential roles in generating innate immune responses, and
are evolutionarily conserved across species. In mammals, TLRs specifically recognize the …

Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle

CM Seabury, PM Seabury, JE Decker… - Proceedings of the …, 2010‏ - pnas.org
The Toll-like receptor (TLR) and peptidoglycan recognition protein 1 (PGLYRP1) genes play
key roles in the innate immune systems of mammals. While the TLRs recognize a variety of …

The polymorphism and haplotype of TLR3 gene in grass carp (Ctenopharyngodon idella) and their associations with susceptibility/resistance to grass carp reovirus

J Heng, J Su, T Huang, J Dong, L Chen - Fish & shellfish immunology, 2011‏ - Elsevier
Toll-like receptors (TLRs) have emerged as crucial sensors of invading microbes through
recognition of pathogen-associated molecular patterns (PAMPs) in viruses, bacteria, fungi …

Functional polymorphisms in Toll-like receptor genes for innate immunity in farm animals

K Novák - Veterinary immunology and immunopathology, 2014‏ - Elsevier
The exploitation of the genetic factors affecting the health status of farm animals represents
an alternative approach to controlling the diseases caused by microbial pathogens. The …