Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022‏ - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Dexamethasone: insights into pharmacological aspects, therapeutic mechanisms, and delivery systems

VS Madamsetty, R Mohammadinejad… - ACS biomaterials …, 2022‏ - ACS Publications
Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment

H Li, R Gou, J Liao, Y Wang, R Qu, Q Tang… - Acta Materia …, 2023‏ - scienceopen.com
Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage
destruction and periarticular bone erosion, thus ultimately compromising joint integrity and …

Nanomedicine is more than a supporting role in rheumatoid arthritis therapy

Y Han, S Huang - Journal of Controlled Release, 2023‏ - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disorder that affects the joints. Various
medications successfully alleviate the symptoms of RA in clinical. Still, few therapy strategies …

Recent advances in targeted drug delivery for treatment of osteoarthritis

S Mehta, T He, AG Bajpayee - Current opinion in rheumatology, 2021‏ - journals.lww.com
Recent years have witnessed significant increase in both fundamental and clinical studies
evaluating DDS for osteoarthritis. Steroid encapsulating polymeric microparticles for longer …

Knee osteoarthritis therapy: recent advances in intra-articular drug delivery systems

L Ma, X Zheng, R Lin, ARJ Sun, J Song… - Drug design …, 2023‏ - Taylor & Francis
Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their
poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …

Nanoparticle-based drug delivery systems for induction of tolerance and treatment of autoimmune diseases

H Li, YG Yang, T Sun - Frontiers in bioengineering and biotechnology, 2022‏ - frontiersin.org
Autoimmune disease is a chronic inflammatory disease caused by disorders of immune
regulation. Antigen-specific immunotherapy has the potential to inhibit the autoreactivity of …

Nanomedicines targeting activated immune cells and effector cells for rheumatoid arthritis treatment

Y Deng, H Zheng, B Li, F Huang, Y Qiu, Y Yang… - Journal of Controlled …, 2024‏ - Elsevier
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
synovial inflammation and inflammatory cellular infiltration. Functional cells in the RA …

[HTML][HTML] Nanomaterial-assisted theranosis of bone diseases

K Zheng, J Bai, H Yang, Y Xu, G Pan, H Wang… - Bioactive Materials, 2023‏ - Elsevier
Bone-related diseases refer to a group of skeletal disorders that are characterized by bone
and cartilage destruction. Conventional approaches can regulate bone homeostasis to a …

Responsive multi‐arm PEG‐modified COF nanocomposites: Dynamic photothermal, pH/ROS dual‐responsive, targeted carriers for rheumatoid arthritis treatment

S Ge, X Wang, X Zhao, L Yuan, X Bao… - Advanced …, 2024‏ - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic immune disease characterized by the infiltration of
immune cells and the proliferation of fibroblast‐like synoviocytes (FLS) at the joint site …