[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Pathological sequelae of long-haul COVID

S Mehandru, M Merad - Nature immunology, 2022 - nature.com
The world continues to contend with successive waves of coronavirus disease 2019 (COVID-
19), fueled by the emergence of viral variants. At the same time, persistent, prolonged and …

[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness

JA Plante, Y Liu, J Liu, H **a, BA Johnson… - Nature, 2021 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …

[HTML][HTML] Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus

B Korber, WM Fischer, S Gnanakaran, H Yoon… - Cell, 2020 - cell.com
A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …

Immunological mechanisms of vaccine-induced protection against COVID-19 in humans

M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …

SARS-CoV-2 infection of the oral cavity and saliva

N Huang, P Pérez, T Kato, Y Mikami, K Okuda… - Nature medicine, 2021 - nature.com
Despite signs of infection—including taste loss, dry mouth and mucosal lesions such as
ulcerations, enanthema and macules—the involvement of the oral cavity in coronavirus …

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda… - Science, 2020 - science.org
The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral …