Biomedical applications of calixarenes: state of the art and perspectives
YC Pan, XY Hu, DS Guo - Angewandte Chemie International …, 2021 - Wiley Online Library
Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …
Molecular recognition with macrocyclic receptors for application in precision medicine
YC Pan, JH Tian, DS Guo - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Macrocyclic receptors can serve as alternatives to natural recognition systems
as recognition tools. They provide effectively preorganized cavities to encapsulate guests …
as recognition tools. They provide effectively preorganized cavities to encapsulate guests …
Drug in drug: a host–guest formulation of azocalixarene with hydroxychloroquine for synergistic anti‐inflammation
S Li, R Ma, XY Hu, HB Li, WC Geng, X Kong… - Advanced …, 2022 - Wiley Online Library
Macrocyclic delivery and therapeutics are two significant topics in supramolecular
biomedicine. The functional integration of these topics would open new avenues for treating …
biomedicine. The functional integration of these topics would open new avenues for treating …
A general hypoxia‐responsive molecular container for tumor‐targeted therapy
TX Zhang, ZZ Zhang, YX Yue, XY Hu… - Advanced …, 2020 - Wiley Online Library
Enhanced drug delivery can improve the therapeutic efficacy of drugs and help overcome
side effects. However, many reported drug‐delivery systems are too complex and …
side effects. However, many reported drug‐delivery systems are too complex and …
Pillararene-based supramolecular systems for theranostics and bioapplications
As an emerging type of important macrocycles for supramolecular chemistry, pillararenes
and their derivatives have been widely studied and applied in numerous fields, which …
and their derivatives have been widely studied and applied in numerous fields, which …
Supramolecular bioimaging through signal amplification by combining indicator displacement assay with Förster resonance energy transfer
WC Geng, Z Ye, Z Zheng, J Gao, JJ Li… - Angewandte …, 2021 - Wiley Online Library
Fluorescent chemosensors are powerful imaging tools in the fields of life sciences and
engineering. Based on the principle of supramolecular chemistry, indicator displacement …
engineering. Based on the principle of supramolecular chemistry, indicator displacement …
Supramolecular radiosensitizer based on hypoxia‐responsive macrocycle
X Hou, YX Chang, YX Yue, ZH Wang, F Ding… - Advanced …, 2022 - Wiley Online Library
Radiotherapy (RT) has been viewed as one of the most effective and extensively applied
curatives in clinical cancer therapy. However, the radioresistance of tumor severely …
curatives in clinical cancer therapy. However, the radioresistance of tumor severely …
Assembling features of calixarene-based amphiphiles and supra-amphiphiles
HW Tian, YC Liu, DS Guo - Materials Chemistry Frontiers, 2020 - pubs.rsc.org
Macrocyclic amphiphiles as an emerging family of artificial amphiphiles have gained
considerable attention in recent years on account of their fascinating recognition and …
considerable attention in recent years on account of their fascinating recognition and …
Cyclodextrin–phytochemical inclusion complexes: Promising food materials with targeted nutrition and functionality
Background Natural phytochemicals suffer from poor aqueous solubility and storage stability
as well as demonstrate limited bioaccessibility; thus, their effectiveness as food ingredients …
as well as demonstrate limited bioaccessibility; thus, their effectiveness as food ingredients …
A host-guest drug delivery nanosystem for supramolecular chemotherapy
XY Hu, J Gao, FY Chen, DS Guo - Journal of Controlled Release, 2020 - Elsevier
Supramolecular chemotherapy is currently a new strategy to improve the therapeutic efficacy
as well as overcome the side effects of traditional chemotherapy. Herein, a supramolecular …
as well as overcome the side effects of traditional chemotherapy. Herein, a supramolecular …