Resting state functional magnetic resonance imaging (rs-fMRI) is based on spontaneous
fluctuations in the blood oxygen level dependent (BOLD) signal, which occur simultaneously …

Aversive motivation plays a prominent role in driving individuals to exert cognitive control.
However, the complexity of behavioral responses attributed to aversive incentives creates …

Light plays a pivotal role in the regulation of affective behaviors. However, the precise
circuits that mediate the impact of light on depressive-like behaviors are not well understood …

Background Ketamine's potent and rapid antidepressant properties have shown great
promise to treat severe forms of major depressive disorder (MDD). A recently hypothesized …

As a critical node connecting the forebrain with the midbrain, the lateral habenula (LHb)
processes negative feedback in response to aversive events and plays an essential role in …

The habenula has been implicated in the pathogenesis of pain and analgesia, while
evidence concerning its function in chronic low back pain (cLBP) is sparse. This study aims …

Despite significant advancements in our understanding of addiction at the neurobiological
level, a highly effective extinction procedure for preventing relapse remains elusive. In this …

The habenula is a small bilateral epithalamic structure that plays a key role in the regulation
of the main monoaminergic systems. It is implicated in many aspects of behavior such as …

The amygdala is an evolutionarily conserved core structure in emotion processing and one
of the key regions of interest in affective neuroscience. Results of neuroimaging studies …

Anhedonia, a pronounced reduction in interest or pleasure in any of life's daily activities, is a
cardinal symptom of major depression. In this Perspective article, we synthesise the recent …