Infectious Diseases Society of America Guidelines on the treatment and management of patients with COVID-19 (April 2020)
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
COVID-19 therapeutics: Small-molecule drug development targeting SARS-CoV-2 main protease
Highlights•The main protease, known as M pro, is encoded by the viral genome and is
essential for viral replication.•The effective target for drug development has been the M …
essential for viral replication.•The effective target for drug development has been the M …
Signaling pathways in macrophages: molecular mechanisms and therapeutic targets
M Li, M Wang, Y Wen, H Zhang, GN Zhao, Q Gao - MedComm, 2023 - Wiley Online Library
Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …
the dysfunction of macrophages is involved in the occurrence and progression of various …
Characterizing long COVID in children and adolescents
Importance Most research to understand postacute sequelae of SARS-CoV-2 infection
(PASC), or long COVID, has focused on adults, with less known about this complex …
(PASC), or long COVID, has focused on adults, with less known about this complex …
Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper
T Marjot, CS Eberhardt, T Boettler, LS Belli… - Journal of …, 2022 - Elsevier
The COVID-19 pandemic has presented a serious challenge to the hepatology community,
particularly healthcare professionals and patients. While the rapid development of safe and …
particularly healthcare professionals and patients. While the rapid development of safe and …
Infectious Diseases Society of America guidelines on the treatment and management of patients with COVID-19 (September 2022)
There are many pharmacologic therapies that are being used or considered for treatment of
coronavirus disease 2019 (COVID-19), with rapidly changing efficacy and safety evidence …
coronavirus disease 2019 (COVID-19), with rapidly changing efficacy and safety evidence …
Long COVID: Clinical characteristics, proposed pathogenesis and potential therapeutic targets
G Kenny, L Townsend, S Savinelli… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence of persistent ill-health in the aftermath of SARS-CoV-2 infection has
presented significant challenges to patients, healthcare workers and researchers. Termed …
presented significant challenges to patients, healthcare workers and researchers. Termed …
Infectious diseases
Microglia, brain-resident innate immune cells, have been extensively studied in
neurodegenerative contexts like Alzheimer's disease. The Coronavirus disease 2019 …
neurodegenerative contexts like Alzheimer's disease. The Coronavirus disease 2019 …
No evidence of clinical efficacy of famotidine for the treatment of COVID-19: a systematic review and meta-analysis
We read with great interest the recent article by Qian et al. that reported paxlovid as an
efficacious treatment for COVID-19 patients. 1 However, the relatively high cost of paxlovid …
efficacious treatment for COVID-19 patients. 1 However, the relatively high cost of paxlovid …
Lots of long COVID treatment leads, but few are proven
L Shaffer - Proceedings of the National Academy of …, 2022 - National Acad Sciences
As the current crisis phase of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) pandemic winds down—and the world nervously awaits potentially dangerous new …
CoV-2) pandemic winds down—and the world nervously awaits potentially dangerous new …