Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption
Y Touitou, A Reinberg, D Touitou - Life sciences, 2017 - Elsevier
Abstract Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …
Melatonin in cancer treatment: current knowledge and future opportunities
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …
experimental studies have documented that melatonin could inhibit different types of cancer …
Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …
progression and metastasis phases. In many cases, the molecular mechanisms …
Melatonin and cancer hallmarks
WH Talib - Molecules, 2018 - mdpi.com
Melatonin is a natural indoleamine produced by the pineal gland that has many functions,
including regulation of the circadian rhythm. Many studies have reported the anticancer …
including regulation of the circadian rhythm. Many studies have reported the anticancer …
Protecting the melatonin rhythm through circadian healthy light exposure
MA Bonmati-Carrion, R Arguelles-Prieto… - International journal of …, 2014 - mdpi.com
Currently, in developed countries, nights are excessively illuminated (light at night), whereas
daytime is mainly spent indoors, and thus people are exposed to much lower light intensities …
daytime is mainly spent indoors, and thus people are exposed to much lower light intensities …
Melatonin: a multitasking molecule
Abstract Melatonin (N-acetyl-5-methoxytryptamine) has revealed itself as an ubiquitously
distributed and functionally diverse molecule. The mechanisms that control its synthesis …
distributed and functionally diverse molecule. The mechanisms that control its synthesis …
Melatonin and its ubiquitous anticancer effects
Abstract Melatonin (N-acetyl-5-methoxy-tryptamine), which is generally considered as
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …
Melatonin: an inhibitor of breast cancer
The present review discusses recent work on melatonin-mediated circadian regulation, the
metabolic and molecular signaling mechanisms that are involved in human breast cancer …
metabolic and molecular signaling mechanisms that are involved in human breast cancer …
Anti-inflammatory effects of Melatonin: A mechanistic review
SM Nabavi, SF Nabavi, A Sureda, J **ao… - Critical reviews in …, 2019 - Taylor & Francis
Abstract N-acetyl-5-methoxy-tryptamine (melatonin) is a natural substance produced both by
plants, as a secondary metabolite, and animals, by the pineal gland and other tissues. In …
plants, as a secondary metabolite, and animals, by the pineal gland and other tissues. In …
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy
Melatonin, the major secretory product of the pineal gland, not only regulates circadian
rhythms, mood, and sleep but also has actions in neoplastic processes which are being …
rhythms, mood, and sleep but also has actions in neoplastic processes which are being …