Chiral separation by enantioselective liquid–liquid extraction

B Schuur, BJV Verkuijl, AJ Minnaard… - Organic & …, 2011 - pubs.rsc.org
The literature on enantioselective liquid–liquid extraction (ELLE) spans more than half a
century of research. Nonetheless, a comprehensive overview has not appeared during the …

Recent progress on chiral extractants for enantioselective liquid-liquid extraction

B Zhu, H Qiu, C Ma, S Chen, J Zhu, S Tong - Journal of Chromatography A, 2023 - Elsevier
As the demand for enantiopure compounds increases, chiral separation has become
increasingly important in many fields. Enantioselective liquid-liquid extraction is an up-and …

[HTML][HTML] Enantioseparation of ofloxacin using a liquid–liquid extraction system based on hydrophobic eutectic solvents

M Moradi, AM Ferreira, CMSS Neves, FHB Sosa… - Separation and …, 2025 - Elsevier
The enantioseparation of chiral drugs is a major challenge for the pharmaceutical industry
as the pharmacological activities of the enantiomers may differ, which can lead to severe …

Experimental and modeling studies on the enantio-separation of 3, 5-dinitrobenzoyl-(R),(S)-leucine by continuous liquid–liquid extraction in a cascade of centrifugal …

B Schuur, JGM Winkelman, JG de Vries… - Chemical engineering …, 2010 - Elsevier
The continuous enantioselective liquid–liquid extraction of aqueous 3, 5-dinitrobenzoyl-
(R),(S)-leucine (AR, S) using O-(1-t-butylcarbamoyl)-11-octadecylsulfinyl-10, 11-dihydro …

Equilibrium studies on enantioselective liquid− liquid amino acid extraction using a cinchona alkaloid extractant

B Schuur, JGM Winkelman… - Industrial & engineering …, 2008 - ACS Publications
The enantioselective extraction of aqueous 3, 5-dinitrobenzoyl-R, S-leucine (AR, S) by a
cinchona alkaloid extractant (C) in 1, 2-dichloroethane was studied at room temperature …

Equilibrium studies on enantioselective extraction of oxybutynin enantiomers by hydrophilic β‐cyclodextrin derivatives

K Tang, P Zhang, C Pan, H Li - AIChE Journal, 2011 - Wiley Online Library
The enantioselective extraction of hydrophobic oxybutynin (OBN) enantiomers by
hydrophilic β‐cyclodextrin (β‐CD) derivatives was studied. The efficiency of extraction …

Continuous chiral separation of amino acid derivatives by enantioselective liquid− liquid extraction in centrifugal contactor separators

B Schuur, J Floure, AJ Hallett… - … Process Research & …, 2008 - ACS Publications
The continuous enantioselective liquid− liquid extraction of aqueous 3, 5-dinitrobenzoyl-d, l-
leucine (DNB-d, l-leu) by a cinchona alkaloid extractant (CA) in 1, 2-dichloroethane using a …

Enantioseparation of chiral aromatic acids in process intensified liquid–liquid extraction columns

A Holbach, J Godde, R Mahendrarajah… - AIChE …, 2015 - Wiley Online Library
Enantioselective liquid–liquid extraction (ELLE) is a powerful alternative to common
technologies for separation of racemic mixtures. The first application of ELLE for aromatic …

Kinetics and mechanism study of lithium extraction from alkaline solution by HFTA and TOPO and strip** process using Lewis cell technique

L Zhang, L Li, D Shi, X Peng, F Song, F Nie - Separation and Purification …, 2019 - Elsevier
The kinetics of forward extraction of lithium from alkaline solution is investigated using a
Lewis cell. Different parameters such as lithium concentration, HFTA concentration, TOPO …

Scalable enantioseparation of amino acid derivatives using continuous liquid− liquid extraction in a cascade of centrifugal contactor separators

B Schuur, AJ Hallett, JGM Winkelman… - … Process Research & …, 2009 - ACS Publications
Using a cascade of six centrifugal contactor separators in a countercurrent liquid− liquid
extraction mode allowed the separation of one of the enantiomers of 3, 5-dinitrobenzoyl …