Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide

J Savitz, WC Drevets - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
Both major depressive disorder and bipolar disorder are the subject of a voluminous
imaging and genetics literature. Here, we attempt a comprehensive review of MRI and …

Insights into myelin dysfunction in schizophrenia and bipolar disorder

M Valdés-Tovar… - World Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Schizophrenia and bipolar disorder are disabling psychiatric disorders with a worldwide
prevalence of approximately 1%. Both disorders present chronic and deteriorating …

Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder

MJ Kempton, JR Geddes, U Ettinger… - Archives of general …, 2008 - jamanetwork.com
Context Despite 25 years of structural imaging in bipolar disorder, brain regions affected in
the disorder are ill defined. Objectives To use meta-analytical techniques to investigate …

Toward constructing an endophenotype strategy for bipolar disorders

G Hasler, WC Drevets, TD Gould, II Gottesman… - Biological …, 2006 - Elsevier
Research aimed at elucidating the underlying neurobiology and genetics of bipolar disorder,
and factors associated with treatment response, have been limited by a heterogeneous …

The node of Ranvier in CNS pathology

IL Arancibia-Carcamo, D Attwell - Acta neuropathologica, 2014 - Springer
Healthy nodes of Ranvier are crucial for action potential propagation along myelinated
axons, both in the central and in the peripheral nervous system. Surprisingly, the node of …

A role for white matter abnormalities in the pathophysiology of bipolar disorder

K Mahon, KE Burdick, PR Szeszko - Neuroscience & Biobehavioral …, 2010 - Elsevier
Bipolar disorder is a chronically disabling psychiatric disorder characterized by manic states
that is often interspersed with periods of depression whose neurobiology remains largely …

Prevalence of white matter hyperintensities in a young healthy population

RO Hopkins, CJ Beck, DL Burnett… - Journal of …, 2006 - Wiley Online Library
ABSTRACT Background and Purpose. White matter hyperintensities (WMHs) are bright
objects observed in the white matter on brain magnetic resonance (MR) imaging. WMHs are …

Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression

WT Regenold, P Phatak, CM Marano, L Gearhart… - Psychiatry …, 2007 - Elsevier
Neuroimaging and postmortem studies suggest the involvement of white matter disease in
schizophrenia, bipolar disorder, and unipolar major depression. To date there is no …

Limbic and corpus callosum aberrations in adolescents with bipolar disorder: a tract-based spatial statistics analysis

N Barnea-Goraly, KD Chang, A Karchemskiy… - Biological …, 2009 - Elsevier
BACKGROUND: Bipolar disorder (BD) is a common and debilitating condition, often
beginning in adolescence. Converging evidence from genetic and neuroimaging studies …

Bipolar disorder and cognitive dysfunction: a complex link

G Cipriani, S Danti, C Carlesi… - The Journal of …, 2017 - journals.lww.com
The aim of this article was to describe the current evidence regarding phenomenon of
cognitive functioning and dementia in bipolar disorder (BD). Cochrane Library and PubMed …