Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

The ABCD study is recruiting and following the brain development and health of over 10,000
9–10 year olds through adolescence. The imaging component of the study was developed …

Background: Several behaviors, besides psychoactive substance ingestion, produce short-
term reward that may engender persistent behavior, despite knowledge of adverse …

Impulsivity and compulsivity represent useful conceptualizations that involve dissociable
cognitive functions, which are mediated by neuroanatomically and neurochemically distinct …

Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …

To better understand the reward circuitry in human brain, we conducted activation likelihood
estimation (ALE) and parametric voxel-based meta-analyses (PVM) on 142 neuroimaging …

Addiction professionals and the public are recognizing that certain nonsubstance behaviors—
such as gambling, Internet use, video-game playing, sex, eating, and shop**—bear …

Altered brain responses to alcohol-associated stimuli are a neural hallmark of alcohol-use
disorder (AUD) and a promising target for pharmacotherapy. However, findings in cue …

Rationale Pathological gambling (PG) has recently been considered as a “behavioral” or
nonsubstance addiction. A comparison of the characteristics of PG and substance use …

'Anticipatory affect'refers to emotional states that people experience while anticipating
significant outcomes. Historically, technical limitations have made it difficult to determine …