The identification of genomic loci that are associated with osteoarthritis (OA) has provided a
starting point for understanding how genetic variation activates catabolic processes in the …

In this review we highlight emerging immune regulatory functions of lumican, keratocan,
fibromodulin, biglycan and decorin, which are members of the small leucine-rich …

Reconstruction of osteochondral (OC) defects represents an immense challenge due to the
need for synchronous regeneration of special stratified tissues. The revolutionary innovation …

We performed a genome-wide association study of total hip replacements, based on
variants identified through whole-genome sequencing, which included 4,657 Icelandic …

Cattle are among the most important domesticated bovid species in the world, of which
Ethiopia possesses large populations adapted to different agro-ecologies and production …

Osteoarthritis is a common, complex disease with no curative therapy. In this review, we
summarize current knowledge on disease aetiopathogenesis and outline genetics and …

Fibrocartilage enthesis is the junction between bone and tendon with a typical
characteristics of fibrocartilage transition zones. The regeneration of this transition zone is …

The accurate and complete assembly of both haplotype sequences of a diploid organism is
essential to understanding the role of variation in genome functions, phenotypes and …

Rubinstein–Taybi syndrome (RSTS) is a rare congenital neurodevelopmental disorder
characterized by growth deficiency, skeletal abnormalities, dysmorphic features, and …

Background Cataract is one of the most common eye diseases that can further cause
blindness. Discovering susceptibility factors contributing to cataract development is helpful …