Recent advances in single cell manipulation and biochemical analysis on microfluidics

D Gao, F **, M Zhou, Y Jiang - Analyst, 2019 - pubs.rsc.org
Single cell analysis has become of great interest with unprecedented capabilities for the
systematic investigation of cell-to-cell variation in large populations. Rapid and multi …

[HTML][HTML] Stem cell-based retina models

K Achberger, JC Haderspeck, A Kleger… - Advanced Drug Delivery …, 2019 - Elsevier
From the early days of cell biological research, the eye—especially the retina—has evoked
broad interest among scientists. The retina has since been thoroughly investigated and …

A 3D printed hanging drop dripper for tumor spheroids analysis without recovery

L Zhao, J **u, Y Liu, T Zhang, W Pan, X Zheng… - Scientific reports, 2019 - nature.com
Compared with traditional monolayer cell culture, the three-dimensional tumor spheroid has
emerged as an essential in vitro model for cancer research due to the recapitulation of the …

Targeted single‐cell therapeutics with magnetic tubular micromotor by one‐step exposure of structured femtosecond optical vortices

L Yang, X Chen, L Wang, Z Hu, C **n… - Advanced Functional …, 2019 - Wiley Online Library
Selective manipulation of specific single cells for therapeutics is important and highly
desirable in biomedical research. As a simple and maneuverable tool, tubular micromotors …

Advances in micro/nanoporous membranes for biomedical engineering

M Sun, K Han, R Hu, D Liu, W Fu… - Advanced healthcare …, 2021 - Wiley Online Library
Porous membrane materials at the micro/nanoscale have exhibited practical and potential
value for extensive biological and medical applications associated with filtration and …

Recent advance in cell patterning techniques: Approaches, applications and future prospects

W Yang, Z Wang, T Yu, Y Chen, Z Ge - Sensors and Actuators A …, 2022 - Elsevier
Cell patterning technology is an effective technique to understand cell behaviors by
precisely controlling the position of cells revealing the major contributions of cells in basic …

[HTML][HTML] Mask-free generation of multicellular 3D heterospheroids array for high-throughput combinatorial anti-cancer drug screening

W Yang, S Cai, Z Yuan, Y Lai, H Yu, Y Wang, L Liu - Materials & Design, 2019 - Elsevier
Since cancer incidence and mortality are rapidly growing worldwide, it is imperative to
develop the effective tumor models in vitro for anti-cancer drug screening. Cellular spheroid …

2D to 3D manipulation and assembly of microstructures using optothermally generated surface bubble microrobots

L Dai, Z Ge, N Jiao, L Liu - Small, 2019 - Wiley Online Library
Hydrogel microstructures that encapsulate cells can be assembled into tissues and have
broad applications in biology and medicine. However, 3D posture control for a single …

[HTML][HTML] Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip

N Sandström, V Carannante, K Olofsson… - Cell Reports …, 2022 - cell.com
Here, we present a methodology based on multiplexed fluorescence screening of two-or
three-dimensional cell cultures in a newly designed multichambered microwell chip …

Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids

O Tartagni, A Borók, E Mensà, A Bonyár… - Cellular and Molecular …, 2023 - Springer
Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with
respect to more traditional 2D culturing. Microwell culturing is a simple and accessible …