Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

The roles of ions on bone regeneration

E O'Neill, G Awale, L Daneshmandi, O Umerah… - Drug discovery today, 2018 - Elsevier
Highlights•Alternative bone regenerative therapeutics are needed.•Ions have been
proposed to regenerate skeletal tissue.•Drug delivery systems have been studied to deliver …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Polysaccharides based biopolymers for biomedical applications: A review

N Jabeen, M Atif - Polymers for Advanced Technologies, 2024 - Wiley Online Library
Polysaccharides are a class of natural biopolymers that have attracted significant attention
due to their unique properties, which make them attractive for use in a wide range of …

Pharmaceutical applications of electrospraying

DN Nguyen, C Clasen, G Van den Mooter - Journal of pharmaceutical …, 2016 - Elsevier
The electrohydrodynamic atomization technique, or simply called electrospraying, has been
extensively studied for biomedical as well as for pharmaceutical applications over the past …

Nanotechnology as a tool to overcome macromolecules delivery issues

LL Tundisi, JA Ataide, JSR Costa… - Colloids and Surfaces B …, 2023 - Elsevier
Nanocarriers can deliver drugs to specific organs or cells, potentially bridging the gap
between a drug's function and its interaction with biological systems such as human …

Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

M Shi, KJ McHugh - Advanced Drug Delivery Reviews, 2023 - Elsevier
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Natural and genetically engineered proteins for tissue engineering

S Gomes, IB Leonor, JF Mano, RL Reis… - Progress in polymer …, 2012 - Elsevier
To overcome the limitations of traditionally used autografts, allografts and, to a lesser extent,
synthetic materials, there is the need to develop a new generation of scaffolds with adequate …

Designer protein delivery: From natural to engineered affinity-controlled release systems

MM Pakulska, S Miersch, MS Shoichet - Science, 2016 - science.org
BACKGROUND Protein therapeutics constitute a multibillion-dollar market, yet their
formulation and sustained delivery still pose a substantial challenge. Controlled release …

Understanding the burst release phenomenon: Toward designing effective nanoparticulate drug-delivery systems

S Bhattacharjee - Therapeutic Delivery, 2021 - Taylor & Francis
Burst release of encapsulated drug with release of a significant fraction of payload into
release medium within a short period, both in vitro and in vivo, remains a challenge for …