Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Nanomaterials for diagnosis and treatment of brain cancer: Recent updates

M Mukhtar, M Bilal, A Rahdar, M Barani, R Arshad… - Chemosensors, 2020 - mdpi.com
Brain tumors, especially glioblastoma, remain the most aggressive form of all the cancers
because of inefficient diagnosis and profiling. Nanostructures, such as metallic …

Inorganic nano-drug delivery systems for crossing the blood–brain barrier: Advances and challenges

Q Tan, S Zhao, T Xu, Q Wang, M Zhang, L Yan… - Coordination Chemistry …, 2023 - Elsevier
The blood–brain barrier (BBB) exists between plasma and brain tissue. It comprises a
capillary wall and glial cells and prevents external substances, including therapeutic agents …

Blood-brain delivery methods using nanotechnology

DM Teleanu, C Chircov, AM Grumezescu, A Volceanov… - Pharmaceutics, 2018 - mdpi.com
Pathologies of the brain, of which brain cancer, Alzheimer's disease, Parkinson's disease,
stroke, and multiple sclerosis, are some of the most prevalent, and that presently are poorly …

Advancements in nanotherapeutics for Alzheimer's disease: current perspectives

S Harilal, J Jose, DGT Parambi, R Kumar… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Considerable progress has been made in the treatment of Alzheimer's disease
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …

New advances in brain-targeting nano-drug delivery systems for Alzheimer's disease

Q Ouyang, Y Meng, W Zhou, J Tong… - Journal of drug …, 2022 - Taylor & Francis
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide and its
incidence is increasing due to the ageing population. Currently, the main limitations of AD …

A reevaluation of chitosan-decorated nanoparticles to cross the blood-brain barrier

H Cortés, S Alcalá-Alcalá, IH Caballero-Florán… - Membranes, 2020 - mdpi.com
The blood-brain barrier (BBB) is a sophisticated and very selective dynamic interface
composed of endothelial cells expressing enzymes, transport systems, and receptors that …

Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery

M Shringarpure, S Gharat, M Momin… - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Epilepsy, a major neurological disorder affects about 1% of the Indian
population. The discovery of noninvasive strategies for epilepsy presents a challenge for the …

Multifunctional Nanotheranostics for Overcoming the Blood–Brain Barrier

M Beygi, F Oroojalian, S Azizi‐Arani… - Advanced Functional …, 2024 - Wiley Online Library
The blood–brain barrier (BBB) is a tailored system of capillary endothelial cells intermixed
with tight junctions and adherent junctions that regulates the transport of various materials …