Alzheimer's disease (AD) is the most frequent type of dementia. The pathological hallmarks
of the disease are extracellular senile plaques composed of beta-amyloid peptide (Aβ) and …

Alzheimer's disease is one of the most devastating neurodegenerative diseases. The exact
cause of the disease is still not known although many scientists believe in the beta amyloid …

Amyloid plaques, the hallmark of Alzheimer's disease (AD), contain fibrillar β-amyloid (Aβ) 1-
40 and 1-42 peptides. Herpes simplex virus 1 (HSV-1) has been implicated as a risk factor …

Senile amyloid plaques are one of the main hallmarks of Alzheimer's disease (AD). They
correspond to insoluble deposits of amyloid-ß peptides (Aß) and are responsible for the …

Sporadic Alzheimer's disease (sAD) is the most common form of dementia. Rats injected
intracerebroventricularly with streptozotocin (STZ-icv) develop insulin-resistant brain state …

Current research including the basic biology of Alzheimer's disease (AD) provides a
foundation to explore whether our current state of knowledge is sufficient to initiate …

Amyloid-β (Aβ) peptides generated by the amyloidogenic pathway of amyloid-β protein
precursor processing contribute significantly to neurodegeneration characteristic of …

Alzheimer's disease (AD) is a neurodegenerative disorder of the central nervous system.
Galectin-3 (Gal-3) is characterized by a conserved sequence within the carbohydrate …

The progressive accumulation of extracellular amyloid plaques in the brain is a common
hallmark of Alzheimer's disease (AD). We recently identified a novel species of Aβ …

Alzheimer's disease (AD) is a major neurodegenerative brain disorder affecting about 14
million people worldwide. Aβ-induced cell injury is a crucial cause of neuronal loss in AD …