The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

Recently, diverse functional materials that take subcellular structures as therapeutic targets
are playing increasingly important roles in cancer therapy. Here, particular emphasis is …

Which scientist has never heard of glutathione (GSH)? This well-known low-molecular-
weight tripeptide is perhaps the most famous natural antioxidant. However, the interest in …

This Perspective focuses on thiol-mediated uptake, that is, the entry of substrates into cells
enabled by oligochalcogenides or mimics, often disulfides, and inhibited by thiol-reactive …

Glutathione has been regarded as a significant signal for distinguishing between tumor and
normal tissue. Recently, reactive oxygen species have attracted much attention for their …

Nucleic acids are a promising type of therapeutic for the treatment of a wide range of
conditions, including cancer, but they also pose many delivery challenges. For efficient and …

A key end goal of gene delivery research is to develop clinically relevant vectors that can be
used to combat elusive diseases such as AIDS. Despite promising engineering strategies …

Graphene oxide has unique physiochemical properties, showing great potential in
biomedical applications. In the present work, functionalized reduced graphene oxide (PEG …

A strategy is reported for controlling the architecture of poly (disulfide) s by ring-opening
polymerization. Aryl thiol initiators shift the ring–chain equilibrium to yield cyclic polymers …