Mitochondria-targeted photodynamic therapy triggers GSDME-mediated pyroptosis and sensitizes anti-PD-1 therapy in colorectal cancer
Y Zhou, W Zhang, B Wang, P Wang… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Background The effectiveness of immune checkpoint inhibitors in colorectal cancer (CRC) is
limited due to the low tumor neoantigen load and low immune infiltration in most …
limited due to the low tumor neoantigen load and low immune infiltration in most …
Intravital imaging of the functions of immune cells in the tumor microenvironment during immunotherapy
X Peng, Y Wang, J Zhang, Z Zhang, S Qi - Frontiers in Immunology, 2023 - frontiersin.org
Cancer immunotherapy has developed rapidly in recent years and stands as one of the most
promising techniques for combating cancer. To develop and optimize cancer …
promising techniques for combating cancer. To develop and optimize cancer …
An anoikis-related gene signature predicts prognosis and reveals immune infiltration in hepatocellular carcinoma
Y Chen, Q Lin, Y Xu, F Qian, C Lin, W Zhao… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a global health burden with poor prognosis.
Anoikis, a novel programmed cell death, has a close interaction with metastasis and …
Anoikis, a novel programmed cell death, has a close interaction with metastasis and …
Association of metabolomics with PD-1 inhibitor plus chemotherapy outcomes in patients with advanced non-small-cell lung cancer
L Zheng, F Hu, L Huang, J Lu, X Yang… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Background Combining immune checkpoint inhibitors (ICIs) with chemotherapy has become
a standard treatment for patients with non-small cell lung cancer (NSCLC) lacking driver …
a standard treatment for patients with non-small cell lung cancer (NSCLC) lacking driver …
Nanobody-armed T cells endow CAR-T cells with cytotoxicity against lymphoma cells
H Wang, L Wang, Y Li, G Li, X Zhang, D Jiang… - Cancer Cell …, 2021 - Springer
Background Taking advantage of nanobodies (Nbs) in immunotherapy, we investigated the
cytotoxicity of Nb-based chimeric antigen receptor T cells (Nb CAR-T) against lymphoma …
cytotoxicity of Nb-based chimeric antigen receptor T cells (Nb CAR-T) against lymphoma …
A novel PD-L1-Containing MSLN targeting vaccine for lung cancer immunotherapy
W Zeng, J Pan, Z Fang, J Jia, R Zhang, M He… - Frontiers in …, 2022 - frontiersin.org
Therapeutic tumor vaccines have become an important breakthrough in the treatment of
various solid tumors including lung cancer. Dendritic cells (DCs)-based tumor vaccines …
various solid tumors including lung cancer. Dendritic cells (DCs)-based tumor vaccines …
Immune Checkpoint Inhibitors for Cancer Therapy: Status and Future Directions
Among various treatment modalities available for the treatment of cancer, immunotherapy is
one of the important strategies used for the management of different malignancies. Immune …
one of the important strategies used for the management of different malignancies. Immune …