Pharmaceutical aspects of salt and cocrystal forms of APIs and characterization challenges
In recent years many efforts have been devoted to the screening and the study of new solid-
state forms of old active pharmaceutical ingredients (APIs) with salification or co …
state forms of old active pharmaceutical ingredients (APIs) with salification or co …
[BOOK][B] Isotope effects in chemistry and biology
A Kohen, HH Limbach - 2005 - taylorfrancis.com
The field of isotope effects has expanded exponentially in the last decade, and researchers
are finding isotopes increasingly useful in their studies. Bringing literature on the subject up …
are finding isotopes increasingly useful in their studies. Bringing literature on the subject up …
Pyridine-15N A Mobile NMR Sensor for Surface Acidity and Surface Defects of Mesoporous Silica
IG Shenderovich, G Buntkowsky… - The Journal of …, 2003 - ACS Publications
The hydrogen bond interaction of pyridine with the silanol groups of the inner surfaces of
MCM-41 and SBA-15 ordered mesoporous silica has been studied by a combination of solid …
MCM-41 and SBA-15 ordered mesoporous silica has been studied by a combination of solid …
Interrogating the Lewis Acidity of Metal Sites in Beta Zeolites with 15N Pyridine Adsorption Coupled with MAS NMR Spectroscopy
The Lewis acidity of isolated framework metal sites in Beta zeolites was characterized with
15N isotopically labeled pyridine adsorption coupled with magic-angle spinning nuclear …
15N isotopically labeled pyridine adsorption coupled with magic-angle spinning nuclear …
How strong is hydrogen bonding in ionic liquids? Combined X-ray crystallographic, infrared/Raman spectroscopic, and density functional theory study
SA Katsyuba, MV Vener, EE Zvereva… - The Journal of …, 2013 - ACS Publications
Hydrogen bonding in ionic liquids based on the 1-(2′-hydroxylethyl)-3-methylimidazolium
cation ([C2OHmim]+) and various anions ([A]−) of differing H-bond acceptor strength, viz …
cation ([C2OHmim]+) and various anions ([A]−) of differing H-bond acceptor strength, viz …
Solid-State Acid−Base Interactions in Complexes of Heterocyclic Bases with Dicarboxylic Acids: Crystallography, Hydrogen Bond Analysis, and 15N NMR …
ZJ Li, Y Abramov, J Bordner, J Leonard… - Journal of the …, 2006 - ACS Publications
A cancer candidate, compound 1, is a weak base with two heterocyclic basic nitrogens and
five hydrogen-bonding functional groups, and is sparingly soluble in water rendering it …
five hydrogen-bonding functional groups, and is sparingly soluble in water rendering it …
Probing Hydrogen Bonding in Cocrystals and Amorphous Dispersions Using 14N–1H HMQC Solid-State NMR
Cocrystals and amorphous solid dispersions have generated interest in the pharmaceutical
industry as an alternative to more established solid delivery forms. The identification of …
industry as an alternative to more established solid delivery forms. The identification of …
Natural Abundance 17O DNP NMR Provides Precise O−H Distances and Insights into the Brønsted Acidity of Heterogeneous Catalysts
Heterogeneous Brønsted acid catalysts are tremendously important in industry, particularly
in catalytic cracking processes. Here we show that these Brønsted acid sites can be directly …
in catalytic cracking processes. Here we show that these Brønsted acid sites can be directly …
OHO hydrogen bond geometries and NMR chemical shifts: from equilibrium structures to geometric H/D isotope effects, with applications for water, protonated water …
HH Limbach, PM Tolstoy… - Israel Journal of …, 2009 - Wiley Online Library
Hydrogen bond geometries and 1 H NMR chemical shifts of OHO hydrogen‐bonded
systems have been analyzed using an improved valence bond order model. This model …
systems have been analyzed using an improved valence bond order model. This model …
Low-temperature NMR studies of the structure and dynamics of a novel series of acid− base complexes of HF with collidine exhibiting scalar couplings across …
IG Shenderovich, PM Tolstoy, NS Golubev… - Journal of the …, 2003 - ACS Publications
The low-temperature 1H, 19F, and 15N NMR spectra of mixtures of collidine-15N (2, 4, 6-
trimethylpyridine-15N, Col) with HF have been measured using CDF3/CDF2Cl as a solvent …
trimethylpyridine-15N, Col) with HF have been measured using CDF3/CDF2Cl as a solvent …